The effect of squash domestication on a belowground tritrophic interaction
The domestication of plants has commonly resulted in the loss of plant defense metabolites, with important consequences for the plants' interactions with herbivores and their natural enemies.
Charlyne Jaccard +6 more
doaj +1 more source
Herbivory reduces plant interactions with above- and belowground antagonists and mutualists. [PDF]
Herbivores affect plants through direct effects, such as tissue damage, and through indirect effects that alter species interactions. Interactions may be positive or negative, so indirect effects have the potential to enhance or lessen the net impacts of
Adler, L.S. +4 more
core +1 more source
Diabrotica speciosa (Germar, 1824) (Coleoptera: Chrysomelidae: Galerucinae) é uma importante praga polífaga na América Latina. Seu controle é realizado com inseticidas sintéticos, o que causa problemas ambientais.
Adriana Yatie Mikami +1 more
doaj +1 more source
Anticancer effects of SH003 and its active component Cucurbitacin D on oral cancer cell lines via modulation of EMT and cell viability. [PDF]
Oral cancer remains a significant global health challenge, as it has high morbidity and mortality rates. Current treatments show limited efficacy and have severe side effects, prompting searches for new therapeutic agents. SH003, a traditional herbal formulation comprising Astragalus membranaceus, Angelica gigas, and Trichosanthes kirilowii, has ...
Choi HS, Ku JK, Ko SG, Yun PY.
europepmc +3 more sources
Grayanotoxin I Intoxication in Pet Pigs [PDF]
Contaminated honey is a common cause of grayanotoxin intoxication in humans. Intoxication of animals, especially cattle, is usually due to ingestion of plants of the Ericaceae family, such as Rhododendron. Here, we report the ingestion of Pieris japonica
Köster, Nils +5 more
core +1 more source
Relationship between triterpenoid anticancer drug resistance, autophagy, and caspase-1 in adult T-cell leukemia [PDF]
We previously reported that the inflammasome inhibitor cucurbitacin D (CuD) induces apoptosis in human leukemia cell lines. Here, we investigated the effects of CuD and a B-cell lymphoma extra-large (Bcl-xL) inhibitor on autophagy in peripheral blood ...
Tsukasa Nakanishi +7 more
doaj +2 more sources
Cucurbitacin E has neuroprotective properties and autophagic modulating activities on dopaminergic neurons [PDF]
Natural molecules are under intensive study for their potential as preventive and/or adjuvant therapies for neurodegenerative disorders such as Parkinson’s disease (PD).
Arel-Dubeau, Anne-Marie +8 more
core +4 more sources
Migrastatics—anti-Metastatic and Anti-invasion Drugs:Promises and Challenges [PDF]
In solid cancers, invasion and metastasis account for more than 90% of mortality. However, in the current armory of anticancer therapies, a specific category of anti-invasion and antimetastatic drugs is missing.
Gandalovičová, Aneta +9 more
core +1 more source
Anti-Cancer Effect of Sesquiterpene and Triterpenoids from Agarwood of Aquilaria sinensis
Two new guaiane sesquiterpenes, aquisinenoids A and B (1 and 2), two new eudesmane-type sesquiterpenoids, aquisinenoids C and D (3 and 4), one new cucurbitacin, aquisinenoid E (5), and five known cucurbitacins (6–10) were isolated from agarwood of ...
Lili Chen +4 more
doaj +1 more source
Background Cucumis prophetarum var. prophetarum is used in Saudi folk medicine for treating liver disorders and grows widely between Abha and Khamis Mushait City, Saudi Arabia.
Abdulrhman Alsayari +5 more
doaj +1 more source

