Results 151 to 160 of about 15,560 (192)

Recent Advances in the Application of Cucurbitacin B as an Anticancer Agent. [PDF]

open access: yesInt J Mol Sci
Yin D   +10 more
europepmc   +1 more source

Cucurbitacin B Inhibits Hepatocellular Carcinoma by Inducing Ferroptosis and Activating the cGAS-STING Pathway. [PDF]

open access: yesCurr Issues Mol Biol
Zhang H   +12 more
europepmc   +1 more source
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Simultaneous determination of cucurbitacin B and cucurbitacin E in rat plasma by UHPLC-MS/MS: A pharmacokinetics study after oral administration of cucurbitacin tablets

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017
Cucurbitacin B (CuB) and cucurbitacin E (CuE) are tetracyclic triterpene compounds from Cucurbitaceae, and the main bioactive compounds of cucurbitacins tablets that used to treatment of chronic hepatitis. Pharmacological research has been very comprehensive, and there are few studies on pharmacokinetics, especially about CuE. An Ultra High Performance
Wenbo Zhu, Chun-Juan Yang, Gaosong Wu
exaly   +3 more sources

Immunomodulatory activity of cucurbitacin E isolated from Ecballium elaterium

Fìtoterapìâ, 2005
The immunomodulatory effect of cucurbitacin E, extracted from Ecballium elaterium, was tested on peripheral human lymphocytes. These lymphocytes were co-cultured with cancer cells and an interesting lymphocyte-mediated cytotoxicity was observed.
Everaldo Attard, Alfred Cuschieri
exaly   +3 more sources

Cucurbitacin E Potently Modulates the Activity of Encephalitogenic Cells

Journal of Agricultural and Food Chemistry, 2016
Cucurbitacin E (CucE) is a highly oxidized steroid consisting of a tetracyclic triterpene. It is a member of a Cucurbitacin family of biomolecules that are predominantly found in Cucurbitaceae plants. CucE has already been identified as a potent anti-inflammatory compound.
Jevtić, Bojan   +5 more
openaire   +5 more sources

Cucurbitacin E: some preliminary observations

Tetrahedron, 1958
Abstract Evidence presented indicates that the functional groupings of cucurbitacin E (α-elaterin) are as follows: an αβ-unsaturated ketone, a 1:2-diketone (enolised), three hydroxyl groups, one of which is acetylated, and probably a further carbonyl group.
J.N.T. Gilbert, David W. Mathieson
openaire   +1 more source

Quantitative determination of cucurbitacin E and cucurbitacin I in homoeopathic mother tincture of Gratiola officinalis L. by HPLC.

Die Pharmazie, 2008
"Hedgehyssop" Gratiola officinalis L. (Scrophulariaceae) is found as an ingredient in homeopathic remedies. Among the active compounds found in G. officinalis, the cucurbitacines constitute a group of triterpenoid substances which are well-known for their bitterness and toxicity.
Melzig, M. F., Kaya, G. I.
openaire   +2 more sources

Cucurbitacin E inhibits the proliferation of glioblastoma cells via FAK/AKT/GSK3β pathway

Oncology Reports, 2023
Glioblastoma (GBM) is the most common primary intracranial tumor in the brain with high growth rate and high mortality rate. Cucurbitacin E (CUE), a tetracyclic triterpene compound derived from species of the genus Cucurbita, has been demonstrated to display significant antitumor effects on various malignancies. In the present study, the effects of CUE
Wen, Chen   +9 more
openaire   +2 more sources

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