Results 151 to 160 of about 15,560 (192)
Recent Advances in the Application of Cucurbitacin B as an Anticancer Agent. [PDF]
Yin D +10 more
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Anticancer effects of SH003 and its active component Cucurbitacin D on oral cancer cell lines via modulation of EMT and cell viability. [PDF]
Choi HS, Ku JK, Ko SG, Yun PY.
europepmc +1 more source
Cucurbitacin B Inhibits Hepatocellular Carcinoma by Inducing Ferroptosis and Activating the cGAS-STING Pathway. [PDF]
Zhang H +12 more
europepmc +1 more source
Cucurbitacin B suppresses glioblastoma via the STAT3/ROS/endoplasmic reticulum stress pathway. [PDF]
Lv G +8 more
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Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, 2017
Cucurbitacin B (CuB) and cucurbitacin E (CuE) are tetracyclic triterpene compounds from Cucurbitaceae, and the main bioactive compounds of cucurbitacins tablets that used to treatment of chronic hepatitis. Pharmacological research has been very comprehensive, and there are few studies on pharmacokinetics, especially about CuE. An Ultra High Performance
Wenbo Zhu, Chun-Juan Yang, Gaosong Wu
exaly +3 more sources
Cucurbitacin B (CuB) and cucurbitacin E (CuE) are tetracyclic triterpene compounds from Cucurbitaceae, and the main bioactive compounds of cucurbitacins tablets that used to treatment of chronic hepatitis. Pharmacological research has been very comprehensive, and there are few studies on pharmacokinetics, especially about CuE. An Ultra High Performance
Wenbo Zhu, Chun-Juan Yang, Gaosong Wu
exaly +3 more sources
Immunomodulatory activity of cucurbitacin E isolated from Ecballium elaterium
Fìtoterapìâ, 2005The immunomodulatory effect of cucurbitacin E, extracted from Ecballium elaterium, was tested on peripheral human lymphocytes. These lymphocytes were co-cultured with cancer cells and an interesting lymphocyte-mediated cytotoxicity was observed.
Everaldo Attard, Alfred Cuschieri
exaly +3 more sources
Cucurbitacin E Potently Modulates the Activity of Encephalitogenic Cells
Journal of Agricultural and Food Chemistry, 2016Cucurbitacin E (CucE) is a highly oxidized steroid consisting of a tetracyclic triterpene. It is a member of a Cucurbitacin family of biomolecules that are predominantly found in Cucurbitaceae plants. CucE has already been identified as a potent anti-inflammatory compound.
Jevtić, Bojan +5 more
openaire +5 more sources
Cucurbitacin E: some preliminary observations
Tetrahedron, 1958Abstract Evidence presented indicates that the functional groupings of cucurbitacin E (α-elaterin) are as follows: an αβ-unsaturated ketone, a 1:2-diketone (enolised), three hydroxyl groups, one of which is acetylated, and probably a further carbonyl group.
J.N.T. Gilbert, David W. Mathieson
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Die Pharmazie, 2008
"Hedgehyssop" Gratiola officinalis L. (Scrophulariaceae) is found as an ingredient in homeopathic remedies. Among the active compounds found in G. officinalis, the cucurbitacines constitute a group of triterpenoid substances which are well-known for their bitterness and toxicity.
Melzig, M. F., Kaya, G. I.
openaire +2 more sources
"Hedgehyssop" Gratiola officinalis L. (Scrophulariaceae) is found as an ingredient in homeopathic remedies. Among the active compounds found in G. officinalis, the cucurbitacines constitute a group of triterpenoid substances which are well-known for their bitterness and toxicity.
Melzig, M. F., Kaya, G. I.
openaire +2 more sources
Cucurbitacin E inhibits the proliferation of glioblastoma cells via FAK/AKT/GSK3β pathway
Oncology Reports, 2023Glioblastoma (GBM) is the most common primary intracranial tumor in the brain with high growth rate and high mortality rate. Cucurbitacin E (CUE), a tetracyclic triterpene compound derived from species of the genus Cucurbita, has been demonstrated to display significant antitumor effects on various malignancies. In the present study, the effects of CUE
Wen, Chen +9 more
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