Squirting Cucumber, Ecballium elaterium (L.) A. Ritch: An Update of Its Chemical and Pharmacological Profile [PDF]
MoleculesEcballium elaterium, also known as squirting cucumber, is a plant which is widespread in temperate regions of Europe, Africa and Asia. The plant is considered to be one of the oldest used drugs. In the last decades, E.
Attilio Anzano +3 more
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Cucurbitacins: Specific Insect Attractants in Cucurbitaceae
Science, 1966 In vivo studies of cucurbitacins, the bitter principles present in Cucurbitaceae, indicated a quantitative relation between the concentrations of cucurbitacin in the plant and the degree of insect feeding. In vitro studies demonstrated the attractiveness of these compounds when they were separated from influences of other components of the host plants.
Oyette, Chambliss L., Jones, Charles M.
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Bioassay-guided isolation of leishmanicidal cucurbitacins from Momordica charantia [PDF]
Frontiers in PharmacologyIntroductionLeishmaniasis, a neglected tropical parasitic disease, is regarded as a major public health problem worldwide. The first-line drugs for leishmaniasis suffer from limitations related to toxicity and the development of resistance in certain ...
Maria Carolina Silva Marques +4 more
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Cucurbitacin IIa Alleviates Colitis via Promoting the Release of Host-Derived Extracellular Vesicles Encapsulating microRNA-30b-5p [PDF]
Journal of Inflammation ResearchYinyin Zhao,1 Binyuan Jiang,2 Shengnan Zuo3 1Ningbo Institute of Innovation for Combined Medicine and Engineering (NIIME), The Affiliated LiHuiLi Hospital of Ningbo University, Ningbo, People’s Republic of China; 2Medical Research Center of the ...
Zhao Y, Jiang B, Zuo S
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Total cucurbitacins from Herpetospermum pedunculosum pericarp do better than Hu-lu-su-pian (HLSP) in its safety and hepatoprotective efficacy [PDF]
Frontiers in PharmacologyThe pericarp of Herpetospermum pedunculosum (HPP) has traditionally been used for treating jaundice and hepatitis. However, the specific hepatoprotective components and their safety/efficacy profiles remain unclear.
Wen-Ya Liu +7 more
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Cucurbitacins as Potent Chemo-Preventive Agents: Mechanistic Insight and Recent Trends
Biomolecules, 2022 Cucurbitacins constitute a group of cucumber-derived dietary lipids, highly oxidized tetracyclic triterpenoids, with potential medical uses. These compounds are known to interact with a variety of recognized cellular targets to impede the growth of ...
Hardeep Singh Tuli +12 more
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Lebensmittelvergiftung durch Cucurbitacine
DMW - Deutsche Medizinische Wochenschrift, 2020 Zusammenfassung Anamnese und klinischer Befund Die 66-jährige Patientin ist wegen einer akuten Lebensmittelvergiftung nach Ingestion von bitteren Zucchini in die Notaufnahme mit Tachykardie, Hypotonie und Somnolenz sowie Exsikkose, Übelkeit, Erbrechen und Hämatochezie eingewiesen worden.
Jung, Carlo +2 more
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First Report on the Occurrence of Cucurbitacins in an Italian Melon Landrace (Cucumis melo L.)
Horticulturae, 2023 Scopatizzo, belonging to the Cucumis melo L., is a local variety of Apulia (Southern Italy), which is consumed as unripe melon as an alternative of cucumber due to its better-quality profile and for the absence of cucurbitacins.
Onofrio Davide Palmitessa +8 more
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The cucurbitacins D, E, and I from Ecballium elaterium (L.) upregulate the LC3 gene and induce cell-cycle arrest in human gastric cancer cell line AGS [PDF]
Iranian Journal of Basic Medical Sciences, 2018 Objective(s): Cucurbitacins exhibit a range of anti-cancer functions. We investigated the effects of cucurbitacins D, E, and I purified from Ecballium elaterium (L.) A.
Naser Jafargholizadeh +2 more
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The effect of squash domestication on a belowground tritrophic interaction
Plant-Environment Interactions, 2022 The domestication of plants has commonly resulted in the loss of plant defense metabolites, with important consequences for the plants' interactions with herbivores and their natural enemies.
Charlyne Jaccard +6 more
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