Results 21 to 30 of about 5,537 (251)
Patrystyczne podstawy personalistyczno-znakowej koncepcji cudu Mariana Ruseckiego
Vox Patrum, 2021 Celem studium jest ukazanie patrystycznych podstaw personalistyczno-znakowej koncepcji cudu ks. profesora Mariana Ruseckiego (1942-2012), najwybitniejszego znawcy tej problematyki w Polsce na przełomie XX i XXI wieku.
Jacenty Mastej
doaj +1 more source
Cuadernos Electrónicos de Filosofía del Derecho, 2023 El artículo aborda la evolución de regulación legal del derecho a las prestaciones sanitarias públicas por parte de migrantes en situación irregular. Se señala el pasaje de un régimen basado en el criterio de la residencia que permitía el acceso a esas ...
Fernando Arlettaz
doaj +3 more sources
Trends in cannabis use disorder and treatment by race and ethnicity, 2002–2019
Frontiers in PsychiatryAims/backgroundAs cannabis use continues to increase in the United States, racialized stereotypes and structural barriers to care might lead to inequitable treatment uptake across racialized groups.
Mireia Triguero Roura +5 more
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Przyroda na usługach świętych na przykładzie św. Feliksa z Noli w "Natalicia" Paulina z Noli
Vox PatrumPo swoim nawróceniu, co roku, na przypadającą 14 stycznia uroczystość św. Feliksa, Paulin z Noli pisał pochwalny utwór na cześć swego Patrona zwany Natalicium. W zachowanych Nataliciach (14 lub 15) ważną rolę odgrywają cuda dokonane przez Feliksa. Wiele
Marcin Wysocki
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Understanding the patient and supporter journey in cocaine use disorder
Frontiers in PsychiatryBackgroundThere is a paucity of literature describing experiences and journey of individuals with cocaine use disorder (CUD) and supporters who care for them.
Denise Leclair +8 more
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source