Results 61 to 70 of about 336,538 (286)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

A gamified online approach to alter Food Cue Reactivity.

open access: yes, 2022
The prevalence of overweight and obesity is rising worldwide, and overweight and obesity are associated with various diseases like diabetes. We need simple interventions targeted at a health-beneficial diet and lowering food cue reactivity (e.g ...
Jonas Potthoff
core   +1 more source

Cue reactivity in cannabis-dependent adolescents. [PDF]

open access: yesPsychology of Addictive Behaviors, 2011
The authors measured event-related potentials with a craving manipulation to investigate the neural correlates of drug cue reactivity in 13 adolescents who are cannabis dependent (CD; ages 14-17). The P300 responses to marijuana (MJ) pictures (MJ-P300) and control pictures (C-P300) were assessed after handling neutral objects and again after handling ...
Lisa D, Nickerson   +6 more
openaire   +2 more sources

The Effect of Hunger and Satiety on Mood-Related Food Craving

open access: yesFrontiers in Psychology, 2020
In addition to hunger, which results from food deprivation, fasting, or restrained eating, food craving is thought to be one of the major factors influencing eating behavior.
Janina Reents   +3 more
doaj   +1 more source

Depicting People in Visual Cues Affects Alcohol Cue Reactivity in Male Alcohol-Dependent Patients

open access: yesBrain Sciences, 2022
Cue reactivity is often used to study alcohol cues brain responses. Standardized image sets are used, but the effect of viewing people interacting with the alcohol drink remains unclear, which is associated with the factors of alcohol cues that influence
Abdulqawi Alarefi   +8 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Cue-Reactivity and Smartphone Dependency

open access: yes, 2021
Objective: Although Cue-Reactivity was originally developed and used with substance addictions, there has been development and validation of cue-reactivity paradigms with behavioral addictions.
Cederstrom, Collytte
core  

The efficacy of cue exposure with response prevention in extinguishing drug and alcohol cue reactivity [PDF]

open access: yes, 2007
It has been suggested that drug cue-elicited urges and psychophysiological reactions are the results of Pavlovian conditioning processes and that it should be possible to extinguish these responses with cue exposure with response prevention.
Jansen, A.T.M.; id_orcid   +6 more
core   +1 more source

Cocaine Cues Used in Experimental Research: A Systematic Review

open access: yesBrain Sciences
Aims: Cue exposure therapy (CET) is a promising treatment approach for cocaine substance use disorder (SUD). CET specifically targets the psychological and physiological responses elicited by drug-related cues, aiming to reduce their motivational impact.
Eileen Brobbin   +14 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

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