Results 51 to 60 of about 13,278 (264)

Extinction of cue-evoked drug-seeking relies on degrading hierarchical instrumental expectancies

, 2014
There has long been need for a behavioural intervention that attenuates cue-evoked drug-seeking, but the optimal method remains obscure. To address this, we report three approaches to extinguish cue-evoked drug-seeking measured in a Pavlovian to ...
Rose, Abigail K., Andrew Jones, Rose, Abigail K, Field, M, Dominic M.D. Tran, Rose, Abigail, Munafò, Marcus R., Munafo, Marcus, Joseph R. Troisi, Tran, Dominic M.D., Troisi, Joseph R, Field, Matt, Marcus R. Munafò, Lee Hogarth, Rose, AK, Munafò, Marcus R, Tran, DM, Tran, DMD, Tran, Dominic M D, Jones, Andrew, Troisi, Joseph, Troisi, Joseph R., Matt Field, Retzler, Chris, Abigail K. Rose, Munafò, MR, Chris Retzler, Hogarth, Lee, Jones, A, Troisi, JR, Hogarth, L, Tran, Dominic, Retzler, C   +32 more
core   +1 more source

Be more mindful: Targeting addictive responses by integrating mindfulness with cognitive bias modification or cue exposure interventions [PDF]

, 2023
This review provides an overview of the most prominent neurocognitive effects of cognitive bias modification (CBM), cue-exposure therapy and mindfulness interventions for targeting addictive responses.
Evers, AWM, Wiers, RW, Hollands, GJ, Larsen, JK, Garland, EL   +4 more
core   +3 more sources

Cannabis cue exposure: a pilot study about extinction contexts

, 2016
Cue-exposure therapy can reduce cravings elicited by conditioned cues such as drug paraphernalia. However, relapse may still occur due to transient reductions in cravings.
Ellise M. Barnier (12310982)
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

The Effect of Repeated Virtual Nicotine Cue Exposure Therapy on the Psychophysiological Responses: A Preliminary Study [PDF]

Psychiatry Investigation, 2011
Smoking related cues may elicit smoking urges and psychophysiological responses in subjects with nicotine dependence. This study aimed to investigate the effect of repeated virtual cue exposure therapy using the surround-screen based projection wall system on the psychophysiological responses in nicotine dependence.The authors developed 3-dimensional ...
Choi, Jung-Seok, Park, Sumi, Lee, Jun-Young, Jung, Hee-Yeon, Lee, Hae-Woo, Jin, Chong-Hyeon, Kang, Do-Hyung   +6 more
openaire   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Cocaine Cues Used in Experimental Research: A Systematic Review

Brain Sciences
Aims: Cue exposure therapy (CET) is a promising treatment approach for cocaine substance use disorder (SUD). CET specifically targets the psychological and physiological responses elicited by drug-related cues, aiming to reduce their motivational impact.
Eileen Brobbin, Natalie Lowry, Matteo Cella, Alex Copello, Simon Coulton, Jerome Di Pietro, Colin Drummond, Steven Glautier, Ceyda Kiyak, Thomas Phillips, Daniel Stahl, Shelley Starr, Lucia Valmaggia, Colin Williams, Paolo Deluca   +14 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Recovered memories of trauma as a special (or not so special) form of involuntary autobiographical memories

Frontiers in Psychology, 2023
Recovered memories of trauma are memories of traumatic events experienced generally during childhood, but of which the persons were unaware until they retrieved it.
Olivier Dodier, Krystian Barzykowski, Céline Souchay   +2 more
doaj   +1 more source

Coping-skills training and cue-exposure therapy in the treatment of alcoholism.

Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism, 2000
Coping-skills training (CST) and cue-exposure treatment (CET) are two relatively new approaches in alcoholism treatment. With CST, the therapist tries to strengthen the patient's skills in coping with situations associated with a high risk of drinking.
P M, Monti, D J, Rohsenow
openaire   +2 more sources