Results 61 to 70 of about 13,278 (264)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Virtual reality interventions in the assessment and treatment of alcohol use disorder - a systematic scoping review on methodology

Addiction Science & Clinical Practice
Background Virtual reality (VR) technology has been increasingly employed to develop innovative treatments for Alcohol use disorder (AUD) and overcome limitations of currents therapies.
Olivia Gaddum, Stefan Gutwinski, Alva Lütt, Daa Un Moon, Anne Beck, Nadja Ruckser, Alessandro Turno, Robert Schöneck, Felix Bermpohl, Nikolaos Tsamitros   +9 more
doaj   +1 more source

A Preliminary Examination of Nicotine-Free Electronic Cigarette Use During Cessation From Combustible Cigarettes

Frontiers in Psychiatry, 2019
Despite the availability of smoking cessation strategies, smoking cue-induced craving remains a relatively untreated relapse risk factor. Utilizing nicotine-free electronic cigarettes (e-cigarettes) to extinguish the motivational influence of smoking ...
Alyssa L. Peechatka, Alyssa L. Peechatka, Elena K. Molokotos, Elena K. Molokotos, Maya Zegel, Scott E. Lukas, Scott E. Lukas, Amy C. Janes, Amy C. Janes   +8 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Changes in dorsomedial striatum activity during expression of goal-directed vs. habit-like cue-induced cocaine seeking

Addiction Neuroscience
A preclinical model of cue exposure therapy, cue extinction, reduces cue-induced cocaine seeking that is goal-directed but not habit-like. Goal-directed and habitual behaviors differentially rely on the dorsomedial striatum (DMS) and dorsolateral ...
Brooke N. Bender, Sierra J. Stringfield, Mary M. Torregrossa   +2 more
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Randomised pilot study of cannabis cue exposure : reducing cue reactivity while building tolerance

, 2018
Objective: Cue-exposure therapy should improve emotion regulation (i.e., reduce cravings and develop tolerance for cravings), but its effects may depend on the context in which it is delivered.
Weidemann, Gabrielle (R15297), Barnier, Ellise, Rapee, Ron M., Chakerian, Kara, Cornish, Jennifer L., Norberg, Melissa M.   +5 more
core   +1 more source

Reminder cues modulate the renewal effect in human predictive learning

Frontiers in Psychology, 2016
Associative learning refers to our ability to learn about regularities in our environment. When a stimulus is repeatedly followed by a specific outcome, we learn to expect the outcome in the presence of the stimulus.
Javier Bustamante, Metin Uengoer, Harald Lachnit   +2 more
doaj   +1 more source