Results 61 to 70 of about 12,300 (122)

Oxytocin Reduces Noradrenergic-Induced Opioid-Like Withdrawal Symptoms in Individuals on Opioid Agonist Therapy

open access: yesBiological Psychiatry Global Open Science
Background: Intranasal administration of the neuropeptide oxytocin has been explored as a potential therapeutic agent for substance use disorder including opioid use disorder (OUD).
Brian J. Gully   +7 more
doaj   +1 more source

NMDA Receptor Modulators in the Treatment of Drug Addiction

open access: yesPharmaceuticals, 2013
Glutamate plays a pivotal role in drug addiction, and the N-methyl-D-aspartate (NMDA) glutamate receptor subtype serves as a molecular target for several drugs of abuse. In this review, we will provide an overview of NMDA receptor structure and function,
M. Foster Olive   +3 more
doaj   +1 more source

Development and Initial Validation of a Rock Climbing Craving Questionnaire (RCCQ)

open access: yesFrontiers in Psychology, 2018
Conceptual similarities have been identified between experiences of extreme sports athletes and those with drug and behavioral addictions. Evidence suggests rock climbers experience craving and other withdrawal-like states when abstinent from their sport.
Gareth Roderique-Davies   +3 more
doaj   +1 more source

Cue Exposure Therapy for Addiction Disorders: A Review of Systematic Reviews

open access: yes, 2021
Mål: Avhengighetsforskningen går for tiden gjennom et paradigmeskifte ved inkluderingen av adferdsavhengighet under avhengighet som paraplybegrep. Forskning har dokumentert nevrobiologiske og erfaringsmessige likheter mellom ulike avhengighetslidelser.
openaire   +1 more source

Distinct neural responses of ventromedial prefrontal cortex-projecting nucleus reuniens neurons during aversive memory extinction

open access: yesMolecular Brain
Animals adaptively regulate aversive memories in safe environments through extinction, a process central to exposure therapy for anxiety disorders.
Yuki Mochizuki   +3 more
doaj   +1 more source

Cigarette craving in virtual reality cue exposure in abstainers and relapsed smokers

open access: yesScientific Reports
Cue exposure therapy (CET) in substance-use disorders aims to reduce craving and ultimately relapse rates. Applying CET in virtual reality (VR) was proposed to increase its efficacy, as VR enables the presentation of social and environmental cues along ...
Benedikt Schröder   +5 more
doaj   +1 more source

Utilizing rewards to dampen fear and its recovery

open access: yesScientific Reports
Fearful memories can be extinguished by repeated exposure, without aversive outcomes. Fear extinction as the basis for exposure therapy, is a common treatment for anxiety and fear-related disorders, but it can be unpleasant and does not always work.
Elliot C. Brown   +4 more
doaj   +1 more source

Craving induction through virtual reality cue-exposure for patients with alcohol dependence in rehabilitation treatment

open access: yesScientific Reports
New therapeutic approaches for alcohol dependence (AD) include virtual reality (VR)-based treatments offering scalable options for cue exposure (CE), a well-established strategy in cognitive behavioral therapy.
N. Tsamitros   +9 more
doaj   +1 more source

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