Results 41 to 50 of about 98,403 (262)

Attention vs. accessibility: the role of different cue types for non-canonical sentence production in German

Frontiers in Language Sciences, 2023
IntroductionThere is evidence of close links between the allocation of attention and the production of language. For instance, while speakers commonly produce active sentences when they describe an event with an agent acting on a patient, this preference
Sarah Dolscheid, Martina Penke
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

Augmentation of self-motion perception with synthetic auditory cues

iScience
Summary: This study tested whether a synthetic auditory cue, designed to encode translational self-motion, can augment vestibular perception. Twenty adults sat on a motion platform and judged whether forward translations were to the left or right of ...
Roie Karni, Adam Zaidel
doaj   +1 more source

Dopamine Encodes Retrospective Temporal Information in a Context-Independent Manner

Cell Reports, 2017
The dopamine system responds to reward-predictive cues to reflect a prospective estimation of reward value, although its role in encoding retrospective reward-related information is unclear.
Kaitlyn M. Fonzi, Merridee J. Lefner, Paul E.M. Phillips, Matthew J. Wanat   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

The traditional experience strategy (TES) and combined ultrasonography examination (CUE) for the treatment of lateral compression type 1 pelvic fractures: a historical control study

BMC Musculoskeletal Disorders, 2021
Background It is difficult to judge the stability of lateral compression type-1 (LC-1) pelvic fracture, as it is often based on static images of the pelvis.
Hai Huang, Bin-Fei Zhang, Ping Liu, Hong-Li Deng, Peng-Fei Wang, Hu Wang, Bao-Feng Li, Yu-Xuan Cong, Yan Zhuang   +8 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Spatiotemporal Variation in Carbon and Water Use Efficiency and Their Influencing Variables Based on Remote Sensing Data in the Nanling Mountains Region

Remote Sensing
A comprehensive evaluation of the variations in carbon use efficiency (CUE) and water use efficiency (WUE) in the Nanling Mountains Region (NMR) is crucial for gaining insights into the intricate relationships between climate change and ecosystem ...
Sha Lei, Ping Zhou, Jiaying Lin, Zhaowei Tan, Junxiang Huang, Ping Yan, Hui Chen   +6 more
doaj   +1 more source