Results 61 to 70 of about 98,403 (262)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Active microbial population dynamics and life strategies drive the enhanced carbon use efficiency in high-organic matter soils

mBio
Microbial carbon use efficiency (CUE) is a critical parameter that controls carbon storage in soil, but many uncertainties remain concerning adaptations of microbial communities to long-term fertilization that impact CUE.
Qicheng Xu, Ling Li, Junjie Guo, Hanyue Guo, Manqiang Liu, Shiwei Guo, Yakov Kuzyakov, Ning Ling, Qirong Shen   +8 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

The Variations of Satellite-Based Ecosystem Water Use and Carbon Use Efficiency and Their Linkages with Climate and Human Drivers in the Songnen Plain, China

Advances in Meteorology, 2019
Ecosystem water use efficiency (WUE) and carbon use efficiency (CUE), as two of the most important ecological indicators of an ecosystem, represent the carbon assimilation rate of unit water consumption and the capacity of transferring carbon from the ...
Bo Li, Fang Huang, Shuai Chang, Ning Sun
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Carbon use efficiency of alpine grasslands affected by grazing exclusion and local environmental context in Tibet, China

Global Ecology and Conservation
Carbon use efficiency (CUE) is essential for understanding how climate change impacts carbon fixation by vegetation across diverse ecosystems globally.
Yunfei Feng, Jianshuang Wu, Meng Li, Ben Chen, Minyahel Tilahun, Xianzhou Zhang   +5 more
doaj   +1 more source

Anticipation of cognitive conflict is reflected in microsaccades: Evidence from a cued-flanker task

Journal of Eye Movement Research, 2019
Microsaccade frequency has recently been shown to be sensitive to high-level cognitive processes such as attention and memory. In the present study we explored the effects of anticipated cognitive conflict. Participants were administered a variant of the
Mario Dalmaso, Luigi Castelli, Giovanni Galfano   +2 more
doaj   +1 more source

Probability Cueing Influences Miss Rate and Decision Criterion in Visual Searches

i-Perception, 2014
In visual search tasks, the ratio of target-present to target-absent trials has an important effect on miss rates. The low prevalence effect indicates that we are more likely to miss a target when it occurs rarely rather than frequently. In this study, we examined whether probability cueing modulates the miss rate and the observer's criterion.
Kazuya Ishibashi, Shinichi Kita
openaire   +3 more sources

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source