Advanced Materials, EarlyView.In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren +6 more
wiley +1 more source
Luminance and attentional modulation of size perception in peripheral vision: Response to Bedell and Johnson. [PDF]
J VisJurkiewicz T, Yeshurun Y, Pisella L.
europepmc +1 more source
A Noninvasive Approach to Study Localized Forces in 3D Epithelia
Advanced Materials, EarlyView.Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand +9 more
wiley +1 more source
From Striatum to Prescription: An Evidence-Based and Bayesian Framework for Neuromotor Rehabilitation in Parkinson's Disease. [PDF]
NeuroSciRossi A, Ginanneschi F.
europepmc +1 more source
Advanced Materials Interfaces, EarlyView.Amphiphilic non‐isocyanate polyurethane (NIPU) coatings containing reactive hydrophobic poly(dimethylsiloxane) (PDMS) and hydrophilic methoxy poly(ethylene glycol) (MPEG) prepolymers for marine antifouling (AF) and fouling‐release (FR) applications were investigated. The coatings were evaluated with a set of representative marine foulants.
Nastaran Shahzadeh +7 more
wiley +1 more source
The Effect of Sex and Gender-Role on Social Attention: Investigating the Association With Social Skills and Academic Preferences. [PDF]
Int J PsycholChacón-Candia JA +3 more
europepmc +1 more source
Bilayered PEDOT:PSS–Collagen Scaffolds as Functional Architectures for Tissue Engineering
Advanced Materials Interfaces, EarlyView.A bilayered scaffold integrates collagen and PEDOT:PSS as distinct yet interconnected 3D matrices, preserving their fibrillar and conductive characteristics. Spatial compartmentalization enables independent tailoring of each domain while maintaining mechanical stability and compatibility with electrochemical monitoring, providing a multifunctional ...
Rasha Nasser +6 more
wiley +1 more source
A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration
Advanced Materials Interfaces, EarlyView.The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani +2 more
wiley +1 more source
Visual cueing and adaptive learning for teaching thyroid eye disease diagnostic assessment to ophthalmology residents. [PDF]
Front Med (Lausanne)Xie J +6 more
europepmc +1 more source
Advanced Materials Technologies, EarlyView.We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang +7 more
wiley +1 more source