Results 71 to 80 of about 1,330,320 (301)

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Enhancing prompt perception in dementia: a comparative study of mixed reality cue modalities

Frontiers in Sports and Active Living
IntroductionDementia impacts millions worldwide and is challenging individuals' ability to engage in daily activities. Active living is crucial in mitigating dementia's neurodegenerative effects, yet people with dementia often struggle to initiate and ...
Shital Desai, Shital Desai, Rupsha Mutsuddi, Rupsha Mutsuddi, Arlene J. Astell, Arlene J. Astell, Arlene J. Astell, Arlene J. Astell   +7 more
doaj   +1 more source

A wolf in sheep's clothing: Predatory fish have convergent consumptive effects but divergent predation‐risk effects

Ecosphere, 2022
Although consumptive effects of predators have long been central to ecology, predation‐risk effects have emerged as major components of predator–prey interactions. Both consumptive and predation‐risk effects should vary with predator functional traits (e.
Jason R. Bohenek, Matthew R. Pintar, Tyler M. Breech, William J. Resetarits Jr   +3 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Use of the tilt cue in a simulated heading tracking task [PDF]

, 1978
The task was performed with subjects using visual-only cues and combined visual and roll-axis motion cues. Half of the experimental trials were conducted with the simulator rotating about the horizontal axis; to suppress the tilt cue, the remaining ...
Junker, A. M., Levison, W. H.
core   +1 more source

What we observe is biased by what other people tell us: beliefs about the reliability of gaze behavior modulate attentional orienting to gaze cues [PDF]

, 2013
For effective social interactions with other people, information about the physical environment must be integrated with information about the interaction partner.
A Frischen, Agnieszka Wykowska, AP Bayliss, B Hommel, C Teufel, C Teufel, CD Frith, CK Friesen, CK Friesen, CK Friesen, E Wiese, E Wiese, EA Hoffman, Eva Wiese, Hermann J. Müller, HJ Müller, J Grezes, J Grezes, J Ristic, J Ristic, J Ristic, J Tipples, L Brothers, L Nummenmaa, MI Posner, MT Liuzza, R Adolphs, R Saxe, RO Deaner, SP Vecera, SRH Langton, Suliann Ben Hamed, U Frith   +32 more
core   +4 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Nonverbal cued in the recognition of affect during imagery

Ψυχολογία: το Περιοδικό της Ελληνικής Ψυχολογικής Εταιρείας, 2020
IS AVAILABLE IN THE ...
Philippos Vanger, Heiner Ellgring
doaj   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source