Results 11 to 20 of about 253,821 (230)

Engineering VIGS Vectors by Modifying Movement Proteins of the 30K Family. [PDF]

open access: yesBiotechnol J
Graphical Abstract and Lay Summary Silencing of plant genes is achieved by inserting small sequences of the target gene into the open reading frame of viral movement proteins belonging to the 30K family. Depending on the size of the insert, the silencing efficiency is around 45% for fragments ranging from 21 to 39 nucleotides, 65% for a 42‐nucleotide ...
Villar-Álvarez D   +3 more
europepmc   +2 more sources

Guidelines for the purification and characterization of extracellular vesicles of parasites

open access: yesJournal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra   +30 more
wiley   +1 more source

Silver‐Based Terpyridine Complexes as Antitumor Agents

open access: yesChemistry – A European Journal, Volume 29, Issue 37, July 3, 2023., 2023
A family of 4’‐X‐terpyridines/tetra‐2‐pyridinylpyrazine silver derivatives with or without phosphines as ancillary ligands has shown high cytotoxicity against different tumour cells. In addition, a great selectivity index has been detected for healthy lymphocytes T in some cases.
María Gil‐Moles   +6 more
wiley   +1 more source

Genomics in neglected and underutilized fruit crops: A chromosome‐scale genome sequence of cherimoya (Annona cherimola)

open access: yesPLANTS, PEOPLE, PLANET, Volume 5, Issue 3, Page 408-423, May 2023., 2023
Cherimoya has been an important food source since Pre‐Columbian times in the Americas. Although it is currently considered an underutilized fruit crop, it is still important at the local level in several regions of Central and South America, and has a clear niche for expansion in regions with subtropical climates.
Alicia Talavera   +4 more
wiley   +1 more source

Electrochemical immunosensing of Growth arrest‐specific 6 in human plasma and tumor cell secretomes

open access: yesElectrochemical Science Advances, Volume 2, Issue 4, August 2022., 2022
Abstract Growth arrest‐specific 6 (GAS6) protein plays a key role in processes related to proliferation, inflammation, angiogenesis, and atherosclerotic plaque formation. In addition, it has been reported that plasma levels of GAS6 are related to cancer prognosis and other relevant pathologies, such as heart failure or sepsis. We report here the first
Cristina Muñoz‐San Martín   +14 more
wiley   +1 more source

Carotenoid fortification of zucchini fruits using a viral RNA vector

open access: yesBiotechnology Journal, Volume 17, Issue 5, May 2022., 2022
Graphical Abstract and Lay Summary Inoculation of zucchini plants with a zucchini yellow mosaic virus (ZYMV) vector that expresses a bacterial phytoene synthase (crtB) induces yellow‐orange fruits that accumulate health‐promoting carotenoids. This is an alternative strategy for metabolic fortification of edible fruits that avoids labor‐intensive and ...
Fakhreddine Houhou   +9 more
wiley   +1 more source

The bacterial effector HopZ1a acetylates MKK7 to suppress plant immunity

open access: yesNew Phytologist, Volume 231, Issue 3, Page 1138-1156, August 2021., 2021
Summary The Pseudomonas syringae type III secretion system translocates effector proteins into the host cell cytosol to suppress plant basal immunity. Effector HopZ1a suppresses local and systemic immunity triggered by pathogen‐associated molecular patterns (PAMPs) and effectors, through target acetylation. HopZ1a has been shown to target several plant
José S. Rufián   +5 more
wiley   +1 more source

Hop stunt viroid: A polyphagous pathogenic RNA that has shed light on viroid–host interactions

open access: yesMolecular Plant Pathology, Volume 22, Issue 2, Page 153-162, February 2021., 2021
This pathogen profile summarizes the current knowledge on Hop stunt viroid, a polyphagous pathogenic RNA that has shed light on significant aspects of viroid–host interactions. Abstract Taxonomy Hop stunt viroid (HSVd) is the type species of the genus Hostuviroid (family Pospiviroidae).
Joan Marquez‐Molins   +2 more
wiley   +1 more source

Implante de condrócitos homólogos em defeitos osteocondrais de cães: padronização da técnica e avaliação histopatológica

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2013
Padronizou-se a metodologia para cultura de condrócitos em cães e avaliou-se seu implante em lesões osteocondrais, utilizando-se a membrana biossintética de celulose (MBC) como revestimento.
L.S. Iamaguti   +7 more
doaj   +1 more source

Meningiomas: An Overview of the Landscape of Copy Number Alterations in Samples from an Admixed Population

open access: yesJournal of Oncology, Volume 2020, Issue 1, 2020., 2020
Meningiomas are considered the most common intracranial tumors, affecting mainly women. Studies in mixed populations can be of great importance to clarify issues related to the genetic diversity of tumors and their development. Considering that data obtained from analyses of the profile of copy number alterations (CNA) have been a useful diagnostic ...
Michele Amaral da Silveira   +7 more
wiley   +1 more source

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