Results 21 to 30 of about 255,189 (216)

Revisão integrativa para substituição do soro fetal bovino por plasma humano rico em plaquetas para cultivo e expansão ex vivo de células humanas destinadas às terapias avançadas

open access: yesVigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2018
Introdução: O avanço dos ensaios clínicos e da terapia celular implicam na necessidade de substituição do soro fetal bovino por um produto de origem humana, capaz de sustentar a expansão de células humanas destinadas às pesquisas e terapias celulares ...
Karla Menezes   +4 more
doaj   +7 more sources

A Betulinic Acid Derivative, BA5, Induces G0/G1 Cell Arrest, Apoptosis Like-Death, and Morphological Alterations in Leishmania sp

open access: yesFrontiers in Pharmacology, 2022
Leishmaniasis are endemic diseases caused by different species of intracellular parasites of the genus Leishmania. Due to the high toxicity and drug resistance of current antileishmanial drugs, it is necessary to identify new and more effective drugs ...
Tatiana Barbosa dos Santos Magalhães   +13 more
doaj   +1 more source

Guidelines for the purification and characterization of extracellular vesicles of parasites

open access: yesJournal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra   +30 more
wiley   +1 more source

Silver‐Based Terpyridine Complexes as Antitumor Agents

open access: yesChemistry – A European Journal, Volume 29, Issue 37, July 3, 2023., 2023
A family of 4’‐X‐terpyridines/tetra‐2‐pyridinylpyrazine silver derivatives with or without phosphines as ancillary ligands has shown high cytotoxicity against different tumour cells. In addition, a great selectivity index has been detected for healthy lymphocytes T in some cases.
María Gil‐Moles   +6 more
wiley   +1 more source

Genomics in neglected and underutilized fruit crops: A chromosome‐scale genome sequence of cherimoya (Annona cherimola)

open access: yesPLANTS, PEOPLE, PLANET, Volume 5, Issue 3, Page 408-423, May 2023., 2023
Cherimoya has been an important food source since Pre‐Columbian times in the Americas. Although it is currently considered an underutilized fruit crop, it is still important at the local level in several regions of Central and South America, and has a clear niche for expansion in regions with subtropical climates.
Alicia Talavera   +4 more
wiley   +1 more source

Electrochemical immunosensing of Growth arrest‐specific 6 in human plasma and tumor cell secretomes

open access: yesElectrochemical Science Advances, Volume 2, Issue 4, August 2022., 2022
Abstract Growth arrest‐specific 6 (GAS6) protein plays a key role in processes related to proliferation, inflammation, angiogenesis, and atherosclerotic plaque formation. In addition, it has been reported that plasma levels of GAS6 are related to cancer prognosis and other relevant pathologies, such as heart failure or sepsis. We report here the first
Cristina Muñoz‐San Martín   +14 more
wiley   +1 more source

CELULAR, PANDEMIA E CONEXÕES À LUZ DA COMUNICAÇÃO E DA CULTURA MATERIAL

open access: yesRevista Latinoamericana de Ciencias de la Comunicación, 2021
No contexto da pandemia de Covid-19, o celular torna-se um objeto de uso para anseios físico-emocionais dos sujeitos, na busca por manter práticas de sociabilidade por conta do isolamento social. Buscou-se analisar o uso do celular por meio das interações entre sujeitos na perspectiva da Cultura Material, o desenvolvimento das subjetividades e os ...
Manuela Do Corral Vieira   +1 more
openaire   +1 more source

Carotenoid fortification of zucchini fruits using a viral RNA vector

open access: yesBiotechnology Journal, Volume 17, Issue 5, May 2022., 2022
Graphical Abstract and Lay Summary Inoculation of zucchini plants with a zucchini yellow mosaic virus (ZYMV) vector that expresses a bacterial phytoene synthase (crtB) induces yellow‐orange fruits that accumulate health‐promoting carotenoids. This is an alternative strategy for metabolic fortification of edible fruits that avoids labor‐intensive and ...
Fakhreddine Houhou   +9 more
wiley   +1 more source

The bacterial effector HopZ1a acetylates MKK7 to suppress plant immunity

open access: yesNew Phytologist, Volume 231, Issue 3, Page 1138-1156, August 2021., 2021
Summary The Pseudomonas syringae type III secretion system translocates effector proteins into the host cell cytosol to suppress plant basal immunity. Effector HopZ1a suppresses local and systemic immunity triggered by pathogen‐associated molecular patterns (PAMPs) and effectors, through target acetylation. HopZ1a has been shown to target several plant
José S. Rufián   +5 more
wiley   +1 more source

Neuroendocrine Mechanisms Underlying Non-breeding Aggression: Common Strategies Between Birds and Fish

open access: yesFrontiers in Neural Circuits, 2021
Aggression is an adaptive behavior that plays an important role in gaining access to limited resources. Aggression may occur uncoupled from reproduction, thus offering a valuable context to further understand its neural and hormonal regulation.
Laura Quintana   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy