Results 11 to 20 of about 7,096,692 (204)

Conditioned Medium from Irradiated Keratinocytes as a Tool for Investigating Communication within the Melano-epidermal Unit. [PDF]

Curr Protoc
Abstract Keratinocytes and melanocytes form the melano‐epidermal unit, whose communication is essential for maintaining the integrity, homeostasis, and functionality of the skin. This interaction is mediated by keratinocytes’ release of various soluble factors, which modulate key processes in melanocytes such as melanogenesis, proliferation, adhesion ...
Zortéa L, Almeida LGG, Filgueira DMVB, Votto APS.   +3 more
europepmc   +2 more sources

DNA Methylation Shapes Seed-Borne Microbiome and Proteome Responses During Early Maize-Beneficial Bacteria Interactions. [PDF]

Plant Cell Environ
ABSTRACT Microorganism and plant interactions are crucial for development and environmental adaptation. Plant growth promoting bacteria enhance agricultural productivity in a sustainable manner, while epigenetic modifications such as DNA methylation regulate gene expression and adaptive responses.
Zocateli PI, Olímpio GV, de Almeida FA, da Rocha LO, de Sena Martins DV, Sangi S, Olivares FL, de Matos EM, Siqueira J, Viccini LF, da Paschoa RP, Silveira V, Grativol C.   +12 more
europepmc   +2 more sources

Engineering VIGS Vectors by Modifying Movement Proteins of the 30K Family. [PDF]

Biotechnol J
Graphical Abstract and Lay Summary Silencing of plant genes is achieved by inserting small sequences of the target gene into the open reading frame of viral movement proteins belonging to the 30K family. Depending on the size of the insert, the silencing efficiency is around 45% for fragments ranging from 21 to 39 nucleotides, 65% for a 42‐nucleotide ...
Villar-Álvarez D, Navarro JA, Pallas V, Sanchez-Navarro JÁ.   +3 more
europepmc   +2 more sources

Guidelines for the purification and characterization of extracellular vesicles of parasites

Journal of Extracellular Biology, Volume 2, Issue 10, October 2023., 2023
Abstract Parasites are responsible for the most neglected tropical diseases, affecting over a billion people worldwide (WHO, 2015) and accounting for billions of cases a year and responsible for several millions of deaths. Research on extracellular vesicles (EVs) has increased in recent years and demonstrated that EVs shed by pathogenic parasites ...
Carmen Fernandez‐Becerra, Patrícia Xander, Daniel Alfandari, George Dong, Iris Aparici‐Herraiz, Irit Rosenhek‐Goldian, Mehrdad Shokouhy, Melisa Gualdron‐Lopez, Nicholy Lozano, Nuria Cortes‐Serra, Paula Abou Karam, Paula Meneghetti, Rafael Pedro Madeira, Ziv Porat, Rodrigo Pedro Soares, Adriana Oliveira Costa, Sima Rafati, Anabela‐Cordeiro da Silva, Nuno Santarém, Christopher Fernandez‐Prada, Marcel I. Ramirez, Dolores Bernal, Antonio Marcilla, Vera Lucia Pereira‐Chioccola, Lysangela Ronalte Alves, Hernando Del Portillo, Neta Regev‐Rudzki, Igor Correia de Almeida, Sergio Schenkman, Martin Olivier, Ana Claudia Torrecilhas   +30 more
wiley   +1 more source

Silver‐Based Terpyridine Complexes as Antitumor Agents

Chemistry – A European Journal, Volume 29, Issue 37, July 3, 2023., 2023
A family of 4’‐X‐terpyridines/tetra‐2‐pyridinylpyrazine silver derivatives with or without phosphines as ancillary ligands has shown high cytotoxicity against different tumour cells. In addition, a great selectivity index has been detected for healthy lymphocytes T in some cases.
María Gil‐Moles, M. Elena Olmos, Miguel Monge, Manuel Beltrán‐Visiedo, Isabel Marzo, José M. López‐de‐Luzuriaga, M. Concepción Gimeno   +6 more
wiley   +1 more source

Genomics in neglected and underutilized fruit crops: A chromosome‐scale genome sequence of cherimoya (Annona cherimola)

PLANTS, PEOPLE, PLANET, Volume 5, Issue 3, Page 408-423, May 2023., 2023
Cherimoya has been an important food source since Pre‐Columbian times in the Americas. Although it is currently considered an underutilized fruit crop, it is still important at the local level in several regions of Central and South America, and has a clear niche for expansion in regions with subtropical climates.
Alicia Talavera, Noe Fernandez‐Pozo, Antonio J. Matas, Jose I. Hormaza, Aureliano Bombarely   +4 more
wiley   +1 more source

Biosynthesis of Silver Nanoparticles Using Black Pepper (Piper nigrum) Seed Extract and Evaluation of Their Cytotoxicity. [PDF]

Chem Biodivers
This study reports the green biosynthesis of piperine‐functionalized silver nanoparticles from Piper nigrum seed extract, followed by comprehensive physicochemical characterization and in vitro cytotoxic evaluation. The results confirm successful nanocomposite formation and demonstrate a marked enhancement of cytotoxic activity against gastric cancer ...
Maciel NF, do Lago GV, da Silva Pereira GV, de Farias Ramos IN, Bastos AC, Barreto IAR, Moraes NS, Dos Santos MN, Pereira da Rocha JA, Machado AK, Junior WGP, da Silva Pessoa MM, Uesugi MNM, Khayat AS, Cruz JN, do Rêgo JA, Joele MRSP, Brasil DDSB.   +17 more
europepmc   +2 more sources

Neuroendocrine Mechanisms Underlying Non-breeding Aggression: Common Strategies Between Birds and Fish

Frontiers in Neural Circuits, 2021
Aggression is an adaptive behavior that plays an important role in gaining access to limited resources. Aggression may occur uncoupled from reproduction, thus offering a valuable context to further understand its neural and hormonal regulation.
Laura Quintana, Cecilia Jalabert, H. Bobby Fokidis, Kiran K. Soma, Kiran K. Soma, Lucia Zubizarreta, Lucia Zubizarreta   +6 more
doaj   +1 more source

Unveiling nuclear localization signals in human arginine deiminase proteins. [PDF]

Protein Sci
Abstract Arginine iminohydrolases are a family of enzymes involved in the conversion of arginine to citrulline. There are five isoforms in humans (PADI1, 2, 3, 4, and 6). Some of them are observed experimentally in the cytoplasm and in the nucleus of the cell; for moving to the latter location, they must pass through the cell nuclear membrane by using ...
Neira JL, Abian O, Velazquez-Campoy A, Rizzuti B.   +3 more
europepmc   +2 more sources

MODELO NUME´RICO MICROMECAˆ NICO PARA SCAFFOLD DE HIDROXIAPATITA COM CULTURA CELULAR [PDF]

Blucher Mechanical Engineering Proceedings, 2014
Nowadays scaffolds and hydroxyapatite biomaterials have been widely used in the biomedical field. The biomechanical engineering is continuously improving methods and materials to analyze and optimize such porous media. The purpose of this article is to implement some methodology discussed in the literature to compare the results of micromechanical with
E. G. F. Mercuri, A. L. Daniel, R. D. Machado, M. B. Hecke   +3 more
openaire   +1 more source