Results 71 to 80 of about 4,591,608 (378)

The anti‐CRISPR protein AcrIE8.1 inhibits the type I‐E CRISPR‐Cas system by directly binding to the Cascade subunit Cas11

FEBS Letters, EarlyView.
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley   +1 more source

Ethnic identity and folk-cultural adaptation: the roles of social distance and social support

Frontiers in Psychology
Multinational states typically face dual challenges arising from ethnic identity and folk-cultural adaptation. Balancing these elements is crucial in social science research.
Ri Hai, Wei Zong, Fang Luo, Fang Luo, Linlin Yang, Xiaoming Bai, Yinbu Suo   +6 more
doaj   +1 more source

The Barthel index: italian translation, adaptation and validation [PDF]

, 2015
The Barthel Index (BI) is widely used to measure disability also in Italy, although a validated and culturally adapted Italian version of BI has not been produced yet.
Castiglia, Sf, Galeoto, G, Lauta, A, Mollica, Roberta, Palumbo, A, Sacchetti, Ml, Santilli, Valter   +6 more
core   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Geographical Factors of Cultural Adaptation in a Diaspora Scenario: Social Kinship Culture in Northern Henan, China

Redai dili
The study of cultural adaptation needs to consider the factors of people and places, and the analysis of "geographical factors" is an important research direction.
Nie Guibo, Hu Han, Ai Shaowei
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Cross-cultural adaptation and reliability testing of Polish adaptation of the European Heart Failure Self-care Behavior Scale (EHFScBS)

Patient Preference and Adherence, 2014
Izabella Uchmanowicz,1 Maria Łoboz-Rudnicka,2 Tiny Jaarsma,3 Krystyna Łoboz-Grudzień1,2 1Department of Clinical Nursing, Wrocław Medical University, Wrocław, Poland; 2Department of Cardiology, T Marciniak Memorial Hospital, Wrocław, Poland; 3Department ...
Uchmanowicz I, Łoboz-Rudnicka M, Jaarsma T, Łoboz-Grudzień K   +3 more
doaj  

Sociocultural adaptation of Chinese international students in the United States and its influencing factors

Frontiers in Psychology
As the number of international Chinese students studying in the US continues to rise and cross-cultural adaptation stress and difficulties they experience may hinder their adaptation culturally, socially, emotionally and academically, understanding their
Xiaofang Wei
doaj   +1 more source

Adaptation to Climate Change and the Role of Agrobiodiversity [PDF]

, 2007
The world’s biological diversity is eroding. This concerns in particular the entire agri-cultural diversity of genes, species and their agrarian ecosystems, the resource base for food. With species becoming extinct, mankind is jeopardised.
Kotschi, Johannes
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source