Results 51 to 60 of about 2,184,076 (288)

Culture and the therapeutic relationship: Perspectives from Chinese clients [PDF]

open access: yes, 2007
Chinese people in the United Kingdom and United States underuse mental health services and, when they do seek help, may find that therapy does not meet their needs. In response to calls in the literature for naturalistic studies of therapy with people of
Jim, J, Pistrang, N
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

An Exploratory Study on the Derivation of Ironical Implicatures by English Foreign Language Learners: Could Culture Play a Role?

open access: yesRevista Alicantina de Estudios Ingleses
Literature on cross-cultural communication has demonstrated that communication breakdowns are more likely to occur among speakers from different cultural backgrounds (Keenan 1976; Devine 1983).
Paola Ortiz Fernández   +1 more
doaj   +1 more source

ENGLISH AS A FOREIGN LANGUAGE. WHAT CHALLENGES DO TEACHERS OF ENGLISH FACE? [PDF]

open access: yesStudia Universitatis Babeş-Bolyai: Geographia, 2016
English as a Foreign Language. What Challenges Do Teachers of English Face? The article undertakes to suggest ways in which English as a foreign language should be taught as a consequence of English becoming a global language and its being spoken in ...
SILVIA IRIMIEA
doaj  

Los Angeles County Arts Commission Cultural Equity and Inclusion Initiative Literature Review [PDF]

open access: yes, 2016
This literature review is intended to investigate and provide background information on how others have addressed the question of improving "diversity in cultural organizations, in the areas of their leadership, staffing, programming and audience ...
Bronwyn Mauldin   +3 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Influential Factors on Clean Food Purchasing Decisions: A Case Study of Consumers in the Lower Northeastern Region of Thailand

open access: yesWorld
This study examines the determinants influencing clean food purchasing decisions among consumers in the lower northeastern region of Thailand. It addresses the significant research gap in understanding the interplay between product attributes, cultural ...
Adisak Suvittawat, Nutchanon Suvittawat
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Cross Cultural Differences Leisure Behavior: The Armenian Community [PDF]

open access: yesSportif Bakış Spor ve Eğitim Bilimleri Dergisi, 2015
In this study, the changing world order, leisure time, are organized according to particular norms of capitalist values and includes a new meaning and usage.
Aytekin Hamdi Başkan, Suat Karaküçük
doaj  

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