Results 91 to 100 of about 845,812 (331)

The Barthel index: italian translation, adaptation and validation [PDF]

, 2015
The Barthel Index (BI) is widely used to measure disability also in Italy, although a validated and culturally adapted Italian version of BI has not been produced yet.
Castiglia, Sf, Galeoto, G, Lauta, A, Mollica, Roberta, Palumbo, A, Sacchetti, Ml, Santilli, Valter   +6 more
core   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Нестандартні підходи до формування лінгвокраїнознавчої компетенції майбутніх учителів іноземної мови (Nonstandard approaches to formation of lingua and country-specific competence of the future foreign language teachers) [PDF]

, 2016
Стаття висвітлює роль мовних центрів у формуванні лінгвокраїнознавчої компетенції майбутніх учителів іноземної мови на прикладі Центру англійської мови та інформації у Київському національному університеті імені Тараса Шевченка та інформаційно ...
Дмитрієва, О. (O. Dmutriieva)
core  

Tourism and Cultural Identity: The Case of the Polynesian Cultural Center [PDF]

Athens Journal of Tourism, 2014
Since Boorstein (1964) the relationship between tourism and culture has been discussed primarily in terms of authenticity. This paper reviews the debate and contrasts it with the anthropological focus on cultural invention and identity. A model is presented to illustrate the relationship between the image of authenticity perceived by tourists and the ...
openaire   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Соціокультурна динаміка діяльності бібліотеки Київського університету імені Бориса Грінченка [PDF]

, 2014
Розглянуто загальні тенденції розвитку вишівських бібліотек як соціокультурних центрів. Проаналізовано соціокультурну складову діяльності бібліотеки Київського університету імені Бориса Грінченка, відзначено позитивну соціокультурну динаміку.Рассмотрены ...
Зотова, Вікторія Анатоліївна, Матвійчук, Оксана Євгенівна   +1 more
core  

Community Center as a Cultural Hub, for Cultural Heritage Conservation

Resourceedings, 2019
Community centers are a type of community development services that promote social relationships and mutual support, develop a sense of self-reliance, social responsibility and community cohesion, as well as empowering individuals and families to solve common social problems.
Yassmin Tony, Darin Refaat, Gehan ElSayed, Aya ElMeligy   +3 more
openaire   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Farm Cultural Park as an urban regeneration lab

Agathón, 2017
A lot of Italian old town centers are wilderness because of their inability to adapt to the different ways of contemporary living and it represents an urgency that needs compelling solutions.
Fausta Occhipinti
doaj   +1 more source