Results 131 to 140 of about 571,184 (317)

Policy to activate cultural change to amplify policy. [PDF]

Proc Natl Acad Sci U S A, 2021
Efferson C.
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Cultural change demands proportionate societal response in the handling of suspected FGM/C cases. [PDF]

Int J Impot Res, 2023
Johnsdotter S, Wendel L.
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Cultural Change and Intercultural Knowledge Creation [PDF]

, 2002
At the beginning of the privatisation the Hungarian freezer manufacturer, Lehel, was acquired by the Swedish Global industry leader, Electrolux. The author of the paper reported on the success and the challenges of the acquisition (Illes and Clarkson ...
Illes, K.
core  

Promoting cultural change towards dementia friendly communities: a multi-level intervention in Japan. [PDF]

BMC Geriatr, 2022
Tsuda S, Inagaki H, Okamura T, Sugiyama M, Ogawa M, Miyamae F, Edahiro A, Ura C, Sakuma N, Awata S.   +9 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Museum mangagement in a time of change : impacts of cultural policy on museums in Britain, 1979-1997 [PDF]

, 1997
This paper examines some of the major impacts of British cultural policy in the 1980s and 1990s, with particular reference to museum management. The paper identifies three major themes of cultural policy at national and local level during the period as
Kawashima, Nobuko
core  

How to detonate a semiotic bomb: the dynamics of Lotmanian explosion in the semiosphere

Language and Semiotic Studies
Lotmanian cultural dynamics involve change through textual interaction. Texts, offering vehicles for information, play a central role in this, with cultural change happening in two modes: gradual and explosive instances of texts that alter the ...
Rodríguez Higuera Claudio Julio
doaj   +1 more source

Advancing a cultural change agenda in higher education: issues and values related to reimagining academic leadership. [PDF]

Discov Sustain, 2022
Whittaker JA, Montgomery BL.
europepmc   +1 more source