Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Advancing a cultural change agenda in higher education: issues and values related to reimagining academic leadership. [PDF]
Whittaker JA, Montgomery BL.
europepmc +1 more source
Sustainable Agriculture in Rural Central American Countries: Grassroots Effectiveness in Initiating Cultural Change [PDF]
This study examines grassroots organizations with respect to their effectiveness in initiating a cultural change in the agricultural practices in Central American countries.
Field, Zach
core +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
How to detonate a semiotic bomb: the dynamics of Lotmanian explosion in the semiosphere
Lotmanian cultural dynamics involve change through textual interaction. Texts, offering vehicles for information, play a central role in this, with cultural change happening in two modes: gradual and explosive instances of texts that alter the ...
Rodríguez Higuera Claudio Julio
doaj +1 more source
Promoting cultural change towards dementia friendly communities: a multi-level intervention in Japan. [PDF]
Tsuda S +9 more
europepmc +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Raw material choices and technical practices as indices of cultural change: Characterizing obsidian consumption at 'Mycenaean' Quartier Nu, Malia (Crete). [PDF]
Carter T, Kilikoglou V.
europepmc +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Involvement and skepticism towards the JCI Accreditation process among hospital's four sectors employees: suggestions for cultural change. [PDF]
Bord S +5 more
europepmc +1 more source

