Results 141 to 150 of about 3,425,802 (309)

Cultural Tradition and Social Change in Agriculture [PDF]

open access: yes, 1990
Bausinger H.   +31 more
core   +1 more source

Culture Change: The Work of C.A. Bowers in Educational Policy [PDF]

open access: yes, 1988
C.A. Bowers has proposed a perspective on educational theory and practice involving cultural literacy and communicative competence. Bowers\u27 proposal addresses culture change through a critical examination of activities in the school curriculum.
Johnson, Nancy R.
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Adaptation to Climate Change and the Role of Agrobiodiversity [PDF]

open access: yes, 2007
The world’s biological diversity is eroding. This concerns in particular the entire agri-cultural diversity of genes, species and their agrarian ecosystems, the resource base for food. With species becoming extinct, mankind is jeopardised.
Kotschi, Johannes
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

INTRODUCTION: “Toward a Socially Progressive Conception of Art Education” [PDF]

open access: yes, 1980
Given the range and subtlety of our cultural conditioning, art education must, of necessity, become critical. It must place critical cultural literacy in the heart of its theory and practice.
Bersson, Robert
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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