Results 111 to 120 of about 6,240,707 (340)

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

City of brave demons: The formation of an urban identity civil code of Ekaterinburg

open access: yesУправление культурой
The formation of a city image is not only one of the key aspects of tourism marketing, a marker of investment attractiveness, but also an important factor in city management.
Alina O. Barsukova, Maria B. Voroshilova
doaj  

THE EFFECTIVENESS OF THE RUSSIAN INTERNATIONAL BROADCASTING IN EUROPE AND USA

open access: yesКонцепт: философия, религия, культура, 2017
The article concerns the effectiveness of the Russian foreign broadcasting in Europe and the United States in 2008-2016. The author analyzes the information campaigns around the South Ossetian conflict (2008) and the Ukrainian crisis (2014-2016); in ...
V. S. Sorokina
doaj  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Decoding Muslim Cultural Code: Oral Poetic Tradition of the Jbala (Northern Morocco)

open access: yesOpen Theology
Spiritual, sometimes directly imbued and sometimes indirectly suggestive of religiosity, poetic genres are common in all corners of the Arab world. While authored religious poetry in Arabic is fairly well studied, oral, unauthored poetic traditions ...
Gintsburg Sarali
doaj   +1 more source

Internet Memes in Network Communication: English Entertainment Sites

open access: yesВиртуальная коммуникация и социальные сети, 2022
Internet memes are an integral part of the Internet entertainment discourse. They are often based on precedent phenomena and reflect current events, facilitate the self-expression of the author, create a comic effect, etc.
Svetlana Yu. Dashkova
doaj  

Cultural and socio-economic restrictions for the adoption of the IESBA code of ethics for professional accountants in the European countries [PDF]

open access: yes, 2015
This paper examines the adoption of the Code of Ethics of the International Ethics Standard Board of Accountants (IESBA) by European accounting organizations.
Barrainkua, Itsaso   +1 more
core  

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