Results 41 to 50 of about 16,519 (241)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Pediatric sarcomas are a heterogeneous group of tumors that contribute disproportionately to cancer mortality in children. Although congenital anomalies are among the strongest known risk factors for childhood cancer, the risk of specific sarcoma subtypes among affected individuals has not yet been thoroughly evaluated. Procedure We
Russ Wolters +17 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Regional Onomastic Vocabulary in Linguaculturological Studies
Вестник Волгоградского государственного университета: Серия 2. Языкознание, 2021 The article considers the possibility of implementing an integrated approach to the representation of a toponym in reference systems and databases, taking its linguistic and cultural specifics into account.
Inna Koroleva
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Reconstructing Linguistic Worldview from Lexical-Semantic Noun Groups in Russian Textbook Exercises
СибСкриптWorldview linguistics extracts lexical-semantic vocabulary from a limited corpus of texts. Such studies were especially popular at the beginning of the 21st century.
Maria V. Surkova
doaj +1 more source
Expression of Human Status Through Animalistic Metaphor
Филологический класс, 2022 The article deals with expression of the status of a person through comparison with animals. Despite the fact that this topic has already been touched upon in one way or another by researchers, not all issues have been resolved yet. The study presents an
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Russian journal of linguistics: Vestnik RUDN, 2018 The article examines cultural semantics of lexical units of the English language through the prism of Anna Wierzbicka’s views. The article focuses on the lexical units like whistle-blower, kangaroo ticket, log cabin president, Camelot presidency, redneck,
Svetlana Viktorovna Ivanova +1 more
doaj +1 more source