Results 61 to 70 of about 103,376 (252)
The relevance of the study is defined by the anthropocentric paradigm of modern linguistics considering phraseological units as means for accumulating and transmitting ethnic culture, which reflect collective experience and mental attitudes of a certain ...
Ekaterina G. Shtyrlina, Yulia V. Ageeva
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
The study identifies the linguodidactic potential of Russian ergonyms in the ritual services sector within the context of teaching Russian lexicology at the university level.
Svetlana Yu. Kamysheva +1 more
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Value Determinants of Financial Threat Perception: Cultural Codes of Economic Behavior of Russians [PDF]
This article presents an empirical study of the value, cognitive, and cultural determinants of financial threat perception and economic behavior among Russians.
Maxim A. LAZAREV, Mikhail G. POLOZKOV
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Cultural codes of the Old Tatar Quarter
Today, Kazan faces the issues of heritage preservation, choosing vectors of development, and the correlation of symbolic and physical space. The important point is to construct its identity in the context of globalization.
Enzhe M. Dusaeva
doaj +1 more source

