Results 71 to 80 of about 828,846 (299)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Encouraging persons to visit cultural sites through mini-games [PDF]
, 2018 Gamification has been recently proposed as a technique to improve user engagement in different activities, including visits to cultural sites and cultural tourism in general.
Catarci, Tiziana +5 more
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Коди культури в образі людини в англомовній картині світу (на матеріалі компаративної фразеології) (Cultural codes in the image of a person in the English language world view (based on the material of the comparative phraseology) [PDF]
, 2016 У статті аналізується на матеріалі компаративних фразеологізмів образ людини в англомовній картині світу крізь призму культурних кодів, а також уточнюються окремі теоретичні питання, пов’язані із означеною темою.
Билиця, У. (U. Bylytsia)
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Russian National Branding: Between Cultural Archetypes and Marketing Strategies
RUDN Journal of Studies in Literature and JournalismThe communicative landscape in contemporary Russia demonstrates a marked turn towards national cultural traditions, folklore, and classical art. Unlike the often opportunistic campaigns in popular culture, branding and marketing communications, due to ...
Anton N. Fortunatov +3 more
doaj +1 more source
Buchi Emecheta : A Novelist\u27s Image of Nigerian Women [PDF]
, 1991 Nigerian novelist Buchi Emecheta writes about the lives of twentieth century Nigerian women. Living during the post-World War II decades of British colonialism, and the subsequent move towards Nigerian Independence in the 1950s, Emecheta\u27s women are ...
Ellsworth, Kirstin Lynne
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source