Results 61 to 70 of about 868,553 (328)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Compendium of Cultural Competence Initiatives in Health Care [PDF]

, 2003
Public and private sector organizations are involved in a number of activities that seek to reduce cultural and communication barriers to health care. These activities are often described as cultural competency and/or cross-cultural education.

core  

International education: a force for peace and cross-cultural understanding? [PDF]

, 2009
This paper discusses the notion that the international sojourn has the potential to transform sojourners into cultural mediators who carry the power to improve global relations.
Arora R., Ball S., Berry J.W., Bochner S., Bock P., Brown L., Daymon C., De Vita G., Detweiler R., Fetterman D., Furnham A., Gaine C., Gilroy P., Gu Q., Gu Q., Gudykunst W., Hofstede G., Hofstede G., Kim Y.Y., Koester J., Kramsch C., Liu M‐C., Lorraine Brown, Martin J., Noy C., Pai H., Piontkowski U., Russell B., Ryan J., Seale C., Sovic S., Spradley J., UKCISA, Ward C., Ward C., Ward C.   +35 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Cultural Competence Interventions for Health Care Providers Working With Racialized Foreign-born Older Adults: Protocol for a Systematic Review [PDF]

, 2022
Diya Chowdhury, Leonardo Baiocco-Romano, Veronica Sacco, Karen El Hajj, Paul Stolee   +4 more
openalex   +1 more source

BUILDING CROSS – CULTURAL COMPETENCE TO IMPROVE ENGLISH EFFECTIVE COMMUNICATION [PDF]

, 2012
This paper is intended to expose the importance of cross-cultural competenc to improve English oral communication effectively. The background of this paper is due to my teaching experience in English Department of School of Bumiayu Islamic Teacher ...
Murtiningsih , Sri
core  

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Cultural Competence and Transcultural Teaching Behaviors and Influencing Factors in Nursing Academia: A Mixed-Methods Study Among Nurse Educators

SAGE Open Nursing
Introduction Cultural competence is crucial in nursing education, with nurse educators playing a key role. However, limited research has explored factors influencing their cultural competence.
Ebtsam Aly Abou Hashish, Hend Alnajjar, Eman Zain Bajamal, Hadeel Abdul Rahman AlJohani, Ranin Ahmed Bahawi   +4 more
doaj   +1 more source

Perceptions from Across the Pond: Building Cultural Competence from Study Abroad Experiences [PDF]

, 2016
At Marquette University, there is a large gap between the number of students who show an interest in studying abroad and those who actually participate in the study abroad process.
Wolff, Kathleen
core   +1 more source

Initial Development and Validation of the Mexican Intercultural Competence Scale [PDF]

, 2013
The current project sought to develop the Mexican Intercultural Competence Scale, which assesses group-specific skills and attributes that facilitate effective cultural interactions, among adults of Mexican descent. Study 1 involved an exploratory factor
Torres, Lucas
core   +2 more sources