Results 161 to 170 of about 339,096 (291)
Nuclear metabolism oscillates during cell cycle progression. Quantitative chromatome proteomics and imaging reveal phase‐specific dynamics of PIP5K1A and nuclear PIP2, linking phosphatidylinositol metabolism to histone methylation. This work identifies nuclear lipid metabolism as a previously unrecognized regulatory axis coordinating chromatin ...
Antoni Gañez‐Zapater +13 more
wiley +1 more source
Mind the (cultural competency) gap: bridging cultural barriers in physiotherapy practice - a quality improvement project. [PDF]
Gohil M, Comer C, Millington PM.
europepmc +1 more source
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
Beyond cultural competency: Applying an antiracism lens to LGBTQ+ care and health. [PDF]
McCadney OK, Levandowski BA.
europepmc +1 more source
The current state of lesbian, gay, bisexual, and transgender cultural competency among U.S. dermatology residents. [PDF]
Nowaskie DZ +2 more
europepmc +1 more source
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance +17 more
wiley +1 more source
Cultural competency education for healthcare professionals: an umbrella review. [PDF]
Lee Y, Sung S, Fan X.
europepmc +1 more source
Correction: How much is needed? Patient exposure and curricular education on medical students' LGBT cultural competency. [PDF]
Nowaskie DZ, Patel AU.
europepmc +1 more source
Ovarian Matrisome Dynamics and αvβ3‐Mediated Regulation in Early Follicular Development
The matrisome undergoes dynamic remodeling during early follicular development. Integrin αvβ3 mediates matrisome signals, regulating primordial follicle activation/atresia and secondary follicle growth via Hippo/mTOR pathways, with conserved roles in human ovaries, offering therapeutic targets for ovarian disorders.
Tong Wu +12 more
wiley +1 more source

