Results 171 to 180 of about 3,861,154 (290)

Chronic HBV Infection Disrupts CCL5‐Secreting cNK Cells and Attenuates Liver Accumulation and Activation of DCs and HBV‐Specific T Cells

Advanced Science, EarlyView.
ADORA2A activation suppresses NFκB‐dependent CCL5 production in cNK cells during chronic HBV infection, disrupting intrahepatic DC recruitment and HBV‐specific CD8+ T‐cell differentiation and function. Targeting the ADORA2A/NFκB/CCL5 axis restores antiviral immunity and facilitates HBV clearance.
Ailu Yang, Yucan Wang, Yating Yu, Jing Wu, Cuiping Bao, Zixuan Wang, Qiuju Han, Zhigang Tian, Jian Zhang, Huajun Zhao   +9 more
wiley   +1 more source

Telemedicine and Cultural Competency in Dementia Care: Mapping Stakeholder Roles in Digital Toolkit Development in SSA: A Systematic Review. [PDF]

Health Expect
Adedeji A, Dogan H, Adedoyin F, Heward M.   +3 more
europepmc   +1 more source

Strategies for Incorporating Health Disparities and Cultural Competency Training into the Pharmacy Curriculum and Co-curriculum. [PDF]

Am J Pharm Educ, 2022
Drame I, Gibson CM, Nonyel NP, Addo-Atuah J, Butler L, Riley A, Kebodeaux C, Henson B, Borja-Hart N.   +8 more
europepmc   +1 more source

SPSB1 Promotes Subcutaneous Adipose Hyperplasia in Facial Port‐Wine Stains by Controlling HDAC1 Degradation and Stability Through Two Distinct Proteolytic Pathways

Advanced Science, EarlyView.
In PWS‐ASPCs, FOSL1 drives the expression of SPSB1. SPSB1, as part of the ESC complex, further binds to HDAC1 and promotes K29‐linked and K48‐linked polyubiquitination of HDAC1. These modifications facilitate the degradation of HDAC1 through the ALP and UPS pathways, respectively.
Hongrui Chen, Bin Sun, Yajing Qiu, Chen Hua, Xiaoxi Lin, Wei Gao   +5 more
wiley   +1 more source

Cultural Competency in Research: A Practical Framework for Use by Researchers, Policymakers, Community Leads and Others When Working With People From Diverse Groups. [PDF]

Health Expect
Stepanova E, Cooper M, Robinson-Barella A, Harris V, Rance A, Husband A, Wright D, Lorencatto F, Tolley C, Tovey W, Wong G, Wong G, Cowie D, Parker K, Crayton E, Nazar H.   +15 more
europepmc   +1 more source

Assessing the LGBT cultural competency of dementia care providers. [PDF]

Alzheimers Dement (N Y), 2021
Nowaskie DZ, Sewell DD.
europepmc   +1 more source

Pyrazole‐Derived Antibacterial Compounds Effectively Treat Methicillin‐Resistant Staphylococcus Aureus Infections by Inhibiting Aspartate Transcarbamoylase

Advanced Science, EarlyView.
This study unveils a novel antibacterial mechanism against MRSA, in which the compound Py‐27 selectively targets and inhibits aspartate transcarbamoylase (ATCase), a key enzyme in pyrimidine synthesis. This inhibition disrupts DNA replication, induces oxidative damage, leading to potent bactericidal activity.
Xiaorong Yang, Xinyuan Cao, Lixia Dai, Feng Yang, Jing Wang, Yudong Ma, Tong Bu, Zile Gong, Xueyan Liu, Changcai Bai, Xiaolou Miao, Xiaofei Shang   +11 more
wiley   +1 more source

Association between the frequency of treating foreign patients and the cultural competency of Japanese healthcare professionals: a mixed-method study. [PDF]

Trop Med Health
Khin YP, Kimura S, Shibata S, Nawa N, Fujiwara T.   +4 more
europepmc   +1 more source

Diversity, Inclusion and Cultural Competency in Pediatric Hospital Medicine Fellowship Programs. [PDF]

Hosp Pediatr, 2021
Dixon G, Barqadle F, Gill E, Okoroafor W, Fromme B, Ganem J.   +5 more
europepmc   +1 more source

Integrated Single‐Cell and TCR Profiling Reveals Protection‐Associated CD8+ T Cell Subsets Linked to Viral Control in PRRSV

Advanced Science, EarlyView.
PRRSV vaccine‐mediated protection is associated with clonally expanded cytotoxic CD8+ T cell subsets driven by viral structural proteins and supported by innate TLR4/TLR8 signaling and CD4+ T cell help, whereas non‐protective responses are characterized by dysfunctional exhausted‐like CD8+ T cells linked to poor viral control.
Can Kong, Siang Chen, Maolin Li, Meng Wang, Hailin Zhang, Bolun Zhou, Zhenhua Xie, Chen Wang, Peng Gao, Jianjun Luo, Hanchun Yang, Runsheng Chen, Dongdong Zhang, Jie Li, Jun Han   +14 more
wiley   +1 more source