Results 211 to 220 of about 6,392,593 (355)

Neighbours and relatives: accounting for spatial distribution when testing causal hypotheses in cultural evolution. [PDF]

Evol Hum Sci, 2023
Bromham L, Yaxley KJ.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Using inclusive fitness and eco-evolutionary theory to model cultural evolution. [PDF]

Evol Hum Behav
Iritani R, West SA.
europepmc   +1 more source

Context congruence: How associative learning modulates cultural evolution. [PDF]

PLoS One, 2023
Tamariz M, Papa A, Cristea M, McGuigan N.   +3 more
europepmc   +1 more source

A STUDY ON EVOLUTION AND DEVELOPMENT OF URBAN REGENERATION WITH EMPHASIS ON THE CULTURAL APPROACH

, 2018
Ali Sharghi, Yousef Jahanzamin, Abdolhamid Ghanbaran, Shahrzad Jahanzamin   +3 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Contrasting modes of cultural evolution: Kra-Dai languages and weaving technologies. [PDF]

Evol Hum Sci
Buckley CD, Kopp E, Pellard T, Ryder RJ, Jacques G.   +4 more
europepmc   +1 more source

Generative cultural learning in children and adults: the role of compositionality and generativity in cultural evolution. [PDF]

Proc Biol Sci, 2023
Varallyay A, Beller N, Subiaul F.
europepmc   +1 more source

Evolution of the Language of Art: Cultural and Artistic Influences [PDF]

, 2018
Oleg A. Krivtsun
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source