Results 131 to 140 of about 5,744,523 (270)

Synergistic p53 Pathway Activation Through Sono‐Gene Therapy Induced by Ultrasound‐Triggered Theranostic Mesoporous Nanoparticles

Advanced Science, EarlyView.
Schematic representation of ultrasound‐mediated ICG/siCD24@MSN‐LCD from nanostructure to synergistic sono‐gene therapy. This nanoplatform targets ASGPR via the LCD shell, which dissociates to release loaded ICG and siCD24. The core mechanism involves ultrasound‐guided sonodynamic therapy by ICG and CD24 knockdown by siCD24, both activating the p53 axis
Yading Zhao, Lu Guo, Dandan Shi, Xiao Sun, Mengmeng Shang, Song Ning, Shuting Huang, Xiaoxuan Wang, Rui Liu, Yuye Fu, Suyun Li, Jie Li   +11 more
wiley   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

Multilingualism in mental health care – a long way to professionalism

Frontiers in Psychiatry
A substantial number of people with mental disorders do not speak the language of their healthcare provider well enough to participate in a full diagnostic procedure or to conduct a cultural formulation interview.
Mike Mösko
doaj   +1 more source

Interview with Bob Winthrop

, 1979
Audio recording and transcript of Bob Winthrop's 1979 interview with Bernard McNicholl for the Coal Tyee History Project. Winthrop shares his memories of the different jobs he had working in both the Extension and Beban Mines. He also talks about what it
Winthrop, Robert
core   +1 more source

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

PENGEMASAN PAKET WISATA CITY TOUR BERBASIS BUDAYA DI KOTA DENPASAR BALI

Jurnal IPTA, 2016
Denpasar city has a variety of tourist potential, namely the potential of cultural tourism such as historical buildings, art attractions, a traditional market with a wide variety of traditional dishes as well as community activities related to culture ...
I Wayan Ary Mahendra Putra, I Made Kusuma Negara, I Putu Sudana   +2 more
doaj  

Patient identity narratives through the cultural formulation interview in a New York City outpatient clinic. [PDF]

Med Anthropol Q, 2023
Aggarwal NK, Chen D, Lewis-Fernández R, Guarnaccia P.   +3 more
europepmc   +1 more source

Adaptation and implementation of the Cultural Formulation Interview and training module for pediatric neuropsychology providers

Applied Neuropsychology: Child
Conceptual frameworks for cultural competence are essential in psychological care. The assessment of implementation efforts in pediatric neuropsychological contexts is particularly lacking. This study investigated an adapted training program for the Cultural Formulation Interview (CFI), including impact on provider cultural competence and perspectives ...
Bianca C, Bondi, Danielle, DuPlessis, Marin M, Taylor, Rivka R, Green, Naddley, Désiré, Tricia S, Williams   +5 more
openaire   +2 more sources

Assignments - A Cultural Awakening at the BCC

, 2013
6th Annual Cultural Arts Festival commemorating the 10th anniversary of the BCC.Front page cover of the program containing a list of activities scheduled for the commemorative celebration.No ...
Purdue University Black Cultural Center
core  

Engineered Brain‐Targeted Exosomes Delivering FGF1 for Sustained Glycemic Regulation and Multitarget Neurovascular Protection in Diabetic Stroke

Advanced Science, EarlyView.
ABSTRACT Diabetic stroke is characterized by a hyperglycemic and pro‐inflammatory microenvironment that exacerbates neurovascular dysfunction. However, the blood–brain barrier (BBB) remains a formidable obstacle, restricting the delivery of most therapeutic molecules.
Bixin Shen, Chengxiang Zhang, Junhui Wang, Xichong Zhong, Shihao Chen, Xue Wang, Xiaokun Li, Li Lin   +7 more
wiley   +1 more source