Results 111 to 120 of about 951,967 (336)

New design approaches to repurposing open educational resources for collaborative learning using mediating artefacts [PDF]

open access: yes, 2009
In spite of high expectations and the support given by prestigious funding and educational institutions, Open Educational Resources (OER) have not been adopted widely by teachers and learners in practice.
Conole, Grainne   +3 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A Cultural-Historical Interpretation of Resilience: the implications for practice

open access: yesOutlines, 2007
Recent attempts at preventing the social exclusion of vulnerable children in England have been driven by notions of resilience which centre primarily on changing children so that they may be better able to cope with adversity.
Anne Edwards, Apostol Apostolov
doaj  

Radical-Transformative Agency: Continuities and Contrasts With Relational Agency and Implications for Education

open access: yesFrontiers in Education, 2019
The recent scholarship on agency is mostly centered around a relational (also known as situative, contextual, distributed, and ecological) approach that draws attention to agency being situated in context and contingent on sociocultural interactivities ...
Anna Stetsenko
doaj   +1 more source

#RhodesMustFall: Using social media to "decolonise" learning spaces for South African higher education institutions: A cultural historical activity theory approach

open access: yesSouth African Journal of Higher Education, 2018
Since the end of 2015, South African universities have been the stage of ongoing student protests that seek to shift the status quo of Higher Education Institutes through calls to decolonise the curriculum and enable free access to HEIs for all. One tool
S. Francis, J. Hardman
semanticscholar   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Unknown Vygotsky: Cultural-Historical Theory in the Context of Pavlov’s Theory of Higher Nervous Activity and H. Werner’s Differential Development Theory

open access: yesКультурно-историческая психология, 2016
The position about the internal connection between the cultural-historical theory of development of higher mental functions of L.S. Vygotsky and two prominent theories of the 20th century is substatianted.
Chuprikova N.I.,
doaj   +1 more source

Math identity and Cultural Historical Activity Theory:

open access: yesOutlines. Critical Practice Studies
The purpose of this exploratory study is to further investigate the cultural contexts under which pre-service teachers develop their mathematics identities. We reviewed pre-service teachers’ mathematics autobiographies that include a description of their math abilities, their perceptions of what it means to be a good student of mathematics and the ...
Socorro Orozco, Aria Razfar
openaire   +1 more source

Current Situation and Future Development of Activity Theory in China [PDF]

open access: yes, 2007
The cultural-historical activity theory was developed by the Russian psychologist Vygotsky and his colleagues in the 1920s and 1930s. Since then, it has been expanded globally and rapidly, particularly during the past 15 years.
Cheng Lehua, Hong Jianzhong, Yang Ning
core   +1 more source

Exploring the Potential of Developmental Work Research and Change Laboratory to Support Sustainability Transformations:A Case Study of Organic Agriculture in Zimbabwe [PDF]

open access: yes, 2018
This paper explores the emergence of transgressive learning in CHAT-informed development work research in a networked organic agriculture case study in Zimbabwe, based on intervention research involving district organic associations tackling ...
McAllister, Georgina   +3 more
core   +2 more sources

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