Results 51 to 60 of about 568,894 (312)

Photographs and history : interpreting past and present through photographs [PDF]

open access: yes, 2019
This book concerns photographs as sources in the research of history and social sciences. The idea is to present various approaches to analyzing both past and present through photographs.

core  

Socio-Economic Development and Infrastructure Cost Performance in China: Comparing Transport and Energy Sectors

open access: yesJournal of Current Chinese Affairs, 2020
Socio-economic development is often linked to efficient infrastructure provision. In China, the government has rolled out ambitious infrastructure projects as part of its national development strategy. There is much to praise about China’s infrastructure
Wiebke Rabe   +2 more
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

The Importance of the Application of Models and Methods to Analyze the Documents in Historical Research [PDF]

open access: yesتاریخ نگری و تاریخ نگاری, 2015
One of the issues concerned in contemporary historical research is neglect of documents and increasing notation of texts in research references. Historical studies because of diversity of sources on the one hand, and changing from dominance of Literary ...
Mohammad Amir Ahmadzadeh
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A multi-analytical approach to identify ancient pigments used in pottery towers excavated from the Han Dynasty tombs

open access: yesHeritage Science, 2023
In 2013, several tombs were discovered and excavated in Southeastern Beijing, China, yielding various burial products. Among these were pottery towers, a representative artifact of the Han Dynasty rarely found in the area.
InHee Go   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Rock Art and Trade Networks: From Scandinavia to the Italian Alps

open access: yesOpen Archaeology, 2020
This article uses rock art to explore potential bonds between Scandinavia and Italy, starting in the second half of the third millennium BCE with the enigmatic Mjeltehaugen burial monument in coastal western Norway and its striking rock art images, and ...
Melheim Lene, Sand-Eriksen Anette
doaj   +1 more source

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