Results 71 to 80 of about 7,153,876 (295)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Assessing the Development in Open Access Publishing in Archaeology: A Case Study From Norway

Open Archaeology
This article examines open access (OA) publishing within archaeology by using Norway as a case study. The authors present data on research publications (n = 1,517) produced by archaeologists at Norwegian universities between 2010 and 2021 and classified ...
Solheim Steinar, Roalkvam Isak, Ødegaard Marie, Loftsgarden Kjetil, Damlien Hege, Vatsvåg Nielsen Svein, Sand-Eriksen Anette, Spangen Marte, Ystgaard Ingrid   +8 more
doaj   +1 more source

The Marabastad Riot, 1942

Contree, 1992
On 28 December 1942 rioting broke out in Marabastad, Pretoria when a wage dispute between the municipality and its African labourers developed into violent confrontation.
J.E.H. Grobler
doaj   +1 more source

From contact lens to 'Dream Lens' - Cultural History of Vision Correction Technology. [PDF]

Uisahak, 2023
Jeong SK.
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Ironmaking and steelmaking process research on Chinese long ring pommel Dao in Han dynasty

Scientific Reports
The long ring pommel Dao (a kind of single-edged blade), a significant indigenous Chinese weaponry innovation of the Western Han Dynasty, is researched this study.
Shen-yang Song, Wei Qian, Xin-tong Lu, Mo-kun Shan   +3 more
doaj   +1 more source

The Chinese in South Africa: A historical study of a cultural minority

Contree, 1999
No abstract available.
Karen L. Harris
doaj   +1 more source

A Bayesian multi-proxy contribution to the socioeconomic, political, and cultural history of late medieval Capitanata (southern Italy). [PDF]

Sci Rep, 2023
Cocozza C, Teegen WR, Vigliarolo I, Favia P, Giuliani R, Muntoni IM, Oione D, Clemens L, Groß M, Roberts P, Lubritto C, Fernandes R.   +11 more
europepmc   +1 more source