Results 61 to 70 of about 568,894 (312)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

New Directions in Social and Cultural History

, 2018
What does it mean to be a social and cultural historian today? In the wake of the 'cultural turn', and in an age of digital and public history, what challenges and opportunities await historians in the early 21st century?
Handley, S, Noakes, L, McWilliam, R
core   +1 more source

Temperature- and humidity-induced changes in alum-treated wood: a qualitative X-ray diffraction study

Heritage Science, 2018
Alum-treated wooden artefacts suffer from extreme deterioration, and the stability of these objects and the salts they contain to variations in climate conditions is an important issue.
Caitlin M. A. McQueen, Calin C. Steindal, Olga Narygina, Susan Braovac   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Practices of Inclusion and Exclusion in Premodern Culture [PDF]

, 2015
In Practices of Inclusion and Exclusion in Premodern Culture a group of Finnish cultural historians discuss the meanings of cultural belonging, experiences and practices of construing boundaries between cultures and their others.
Holmberg, Eva Johanna, Linkinen, Tom (toim.)   +1 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Enculturating Coastal Environments in the Middle Mesolithic (8300–6300 cal BCE) – Site Variability, Human–Environment Relations, and Mobility Patterns in Northern Vestfold, SE-Norway

Open Archaeology, 2022
The coastal settlement in Middle Mesolithic (MM) Southeast Norway is generally described as a dynamic system of small, short-lived sites and large sites that were visited repeatedly over a long time.
Berg-Hansen Inger Marie, Hårstad Silje, Granados Tina J., Reitan Gaute, Romundset Anders, Johannessen Linnea S., Solheim Steinar   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

New perspective on Jun glaze corrosion: study on the corrosion of light greenish blue and reddish purple glazes from Juntai Kiln, Yuzhou, Henan, China

Heritage Science, 2020
The ancient Chinese Jun Porcelain has of typical high fired calcium silicate glaze. After observation of Jun porcelain shards excavated from Juntai Kiln in Yuzhou, Henan Province, China, two pieces with light greenish blue glaze and reddish purple glaze ...
Zhimin Li, Ying Ma, Qinglin Ma, Jiachang Chen, Yan Song   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source