Results 81 to 90 of about 1,795,391 (358)

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

REPRESENTATION OF CULTURAL IDENTITY IN LIMAS HOUSE PALEMBANG

open access: yesDimensi: Journal of Architecture and Built Environment, 2021
This study analyzes the limas house as reflect of Palembang cultural identity, which is interpreted as the identity of "as to becoming". The change in the limas house as a cultural marker is adaptive and dynamic following changes in cultural identity ...
Dadang Hikmah Purnama   +2 more
doaj   +1 more source

Telling another story: western museums and the creation of non-western identity [PDF]

open access: yes, 2010
The present paper is based upon the idea of Western museums as informal cultural forums. Specifically, it is concerned with Western museums, non- Western collections and the formation of local identity.
Catalani, A
core  

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

open access: yesMolecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens   +8 more
wiley   +1 more source

"Culture of Identity" and "Identity of Culture"

open access: yesPhilological studies (Skopje), 2010
In this paper I am interested in special relation between individual aspect of culture which is connected with identity, forms and narrative discourses that establishes it and the issue of common culture, reference to social aspects of culture. Problems between individual identity and common culture are complex and interlaced ; what is more, their ...
openaire   +1 more source

International Trade and Cultural Identity [PDF]

open access: yes
Economists emphasize the benefits from free trade due to international specialization, but typically have a narrow measure of what matters to individuals.
Eckhard Janeba
core  

Different coloured tears: Dual cultural identity and Tangihanga [PDF]

open access: yes, 2011
Although whānau/family that are configured by both Pākehā and Māori identities number significantly within New Zealand, there has been little or no attention paid to the ways in which these identities influence the bereavement processes that will ...
Edge, Kiri   +2 more
core   +1 more source

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

A comparative study of circulating tumor cell isolation and enumeration technologies in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells were spiked into donor blood to evaluate the recovery rates of the following circulating tumor cell (CTC) enrichment technologies: CellMag™, EasySep™, RosetteSep™, Parsortix® PR1, and Parsortix® Prototype systems. Each method's advantages and disadvantages are described.
Volga M Saini   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy