Results 121 to 130 of about 779,176 (289)

Cross-Cultural Responses to Digital Guides in Authoritarian Heritage: A Case Study of the Chiang Kai-Shek Memorial Hall

open access: yesHeritage
Over the past two decades, transitional justice has become a central concern in Taiwan’s cultural and political landscape. This study investigates how 1029 visitors from Taiwan, Sinophone regions (China, Hong Kong, Macau, Malaysia), and international ...
Chan-Li Lin
doaj   +1 more source

Productivity Growth in Canadian and U.S. Regulated Industries [PDF]

open access: yes
This article compares the productivity growth of a set of Canadian and U.S. regulated industries. Using data from Statistics Canada’s KLEMS database and the U.S.
Amélie Lafrance, Wulong Gu
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Regional Distribution of Creative and Cultural Industries in Indonesia [PDF]

open access: yes, 2015
This study examines the degree to which creative industries fit regional economic settings in the developing world. In so doing, we examine the characteristics of regions where clusters of these industries are found, particularly in Indonesia.
Fahmi, Fikri Zul
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

@rtec: art and technology in the cultural industries [PDF]

open access: yes, 2004
The @rtec project – Art and Technology in the Cultural Industries – is co-financed by InterReg IIIA and its partners are the Bienal de Vila Nova de Cerveira (Biennial of Vila Nova de Cerveira), the Centro Cultural de Deputación de Ourense (Cultural ...
Castro, Rui   +4 more
core  

The Application of AHP Model to Guide Decision Makers: A Case Study of E-banking Security

open access: yes, 2009
Changes in technology have resulted in new ways for bankers to deliver their services to costumers. Electronic banking systems in various forms are the evidence of such advancement.
Hwang, Junseok, Syamsuddin, Irfan
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

The city mouse and the country mouse: the geography of creativity and cultural production in Italy [PDF]

open access: yes
Through census employment data we analyze the evolving structure of the Italian cultural economy and highlights diverging spatial and organizational patterns of cultural production systems in urban and regional areas.
Bertacchini Enrico, Borrione Paola
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

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