Results 101 to 110 of about 83,750 (298)

Real-time sensor networks based on genetic algorithms application in the analysis of innovative data in cultural industry management

open access: yesMeasurement: Sensors
Against the backdrop of sustained economic development and steady improvement of China's overall national strength, the cultural industry is in a good stage of development, but it also faces problems such as data complexity and difficulty in organizing ...
Baohui Zhang   +3 more
doaj  

O "Grande Irmão" e a empresa: indústria cultural, reality shows e espetáculos organizacionais

open access: yesCadernos EBAPE.BR
A motivação para este ensaio relaciona-se à busca de uma via mais direta de comunicação entre pesquisadores descontentes e participantes organizacionais pouco identificados com leituras críticas e mais interessados em render homenagem a certos produtos ...
Marcos Goulart Castelo   +1 more
doaj   +1 more source

Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management

open access: yesMolecular Oncology, EarlyView.
DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez   +5 more
wiley   +1 more source

Raphin‐1 mediates the survival and sensitivity to radiation of pediatric‐type diffuse high‐grade glioma via phosphorylated eukaryotic initiation factor 2α‐dependent and ‐independent processes

open access: yesMolecular Oncology, EarlyView.
Raphin‐1 reduces the survival of PED‐DHGG cells and enhances their radiation sensitivity through both PeIF2α‐dependent and PeIF2α‐independent mechanisms. Raphin‐1 sustains elevated levels of PeIF2α, contributing to its PeIF2α‐dependent effects. Additionally, raphin‐1 interacts with CReP to mediate a separate radiosensitizing pathway that operates ...
Karin Eytan   +4 more
wiley   +1 more source

Targeting carbonic anhydrase IX/XII prevents the anti‐ferroptotic effect of stromal lactic acid in prostate carcinoma

open access: yesMolecular Oncology, EarlyView.
In prostate carcinoma, lactic acid, secreted by highly glycolytic cancer‐associated fibroblasts, is imported into tumor cells through the MCT1 transporter and prevents RSL3 and erastin‐induced ferroptosis (A). Targeting of carbonic anhydrase IX/XII, the main extracellular pH regulators, in tumor and stromal cells reduces microenvironmental acidosis and
Elisa Pardella   +18 more
wiley   +1 more source

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