Results 101 to 110 of about 1,539,709 (312)
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Innovation and Integration Development of the Cultural Industry Based on Mapping Knowledge Domains. [PDF]
Comput Intell Neurosci, 2022 Lian J, Liang D.
europepmc +1 more source
ESTETIKA POSMODERN DALAM PARIWISATA : KOMODIFIKASI KESENIAN BALI [PDF]
, 2003 Balinese arts can be said one of the most important entities in the system of tourism industry in Bali. However, due to the business maximalization of the industry, the Balinese arts are commodified (getting a “commodification” , that is a process of ...
I Gede, Mudana
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KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Between plumbers and mushrooms. The cinema adaptation of the classic videogame Super Mario Bros
Doxa ComunicaciónIn this article, cinema and video games converge with the aim of analyzing the audiovisual treatment of the characters who acquire an important role in the film Super Mario Bros: The Movie (Horvarth and Jelenic, 2023) and the transformations raised with
María Nieves Corral Rey +1 more
doaj +1 more source
The book an adaptation from the film: technology, narrative, business & how the book industry might adapt the film [PDF]
, 2011 This paper proposes that the book, both its form and the book publishing industry that support it can make reference to how the film industry have reacted to technological change since the 1980 's.
Ayodeji, J
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Cultural Effects of Trade Liberalization [PDF]
We incorporate culture into a standard trade model in two distinct ways. In the ¡°cultural affinity from work¡± model, workers receive a non- pecuniary cultural benefit from work in a particular industry.
Robert Winthrop, Steven M. Suranovic
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