Results 91 to 100 of about 4,676,992 (300)
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
FEBS Open Bio, EarlyView.Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Increasing Local Economic Via Developing Tourism Trail at Sungai Budor Village, Kelantan [PDF]
BIO Web of ConferencesDeveloping a tourism trail can significantly boost the local economy by leveraging the village’s unique cultural, historical, and natural assets to attract visitors.
Hasan Ramly +6 more
doaj +1 more source
Cultural Landscape Areas: Documentation, Preservation Treatments, and Design Interventions
, 2014 110 pagesThis is the second studio project directed to documenting understanding preserving and enhancing Nuestra Senora Reina de la Paz (La Paz) in Keene, California.
Lewis, Alison +9 more
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Greenways as strategic landscape planning: theory and application [PDF]
, 2002 Greenways are systems and/or networks of protected lands that are managed for multiple uses including: nature protection, biodiversity management, water resources, recreation, and cultural/historic resource protection.
Ahern, J.F.
core
FEBS Open Bio, EarlyView.Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia +9 more
wiley +1 more source
Cell surface CD11c as a neutrophil aging marker molecule
FEBS Open Bio, EarlyView.Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki +5 more
wiley +1 more source
Model of interaction of geographic, cultural and sacral landscapes
Неофилология, 2015 The interaction of geographical, cultural and sacred landscapes is considered. The concept “landscape” is analyzed and its interdisciplinary character is emphasized. It is proposed to divide the definition of phenomenon on the concept “theoretical models”
Nataliya Nikolaevna LAVRINOVA
doaj
The Appalachian cultural landscape along the New River
, 2009 The regional landscape of Appalachian was a testing ground for a method to define cultural landscape. Landscape Architects and land planners can learn from the existing landscape about the aesthetics and environmental constraints of an area to design and
Mellen, E. Garnett
core
Cultural landscape: a new paradigm for landscape architecture [PDF]
, 2011 This paper presents the review on the important of cultural landscape in the context of landscape architecture’s profession. It is crucial to understand the concept of cultural landscape as it offers main contribution in sustaining the heritage value and
Md Jani, Haza Hanurhaza +1 more
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