Results 81 to 90 of about 72,601 (261)

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Engagement Patterns With an Artificial Intelligence Health Coach for Systemic Sclerosis Self‐Management: A Mixed Methods Study

Arthritis Care &Research, EarlyView.
Objective To evaluate utility of an artificial intelligence (AI) health coach for systemic sclerosis (SSc) self‐management and identify patterns associated with participant engagement. Methods We conducted a mixed methods study in which an AI health coach, powered by a large language model (LLM), was used to support self‐management for SSc.
Nirali Shah, Melanie Morris, Cristina Daraban, Sophia Johnson, Susan L. Murphy   +4 more
wiley   +1 more source

Application of 4D Technologies in Heritage: A Comprehensive Review

Buildings
Three-dimensional (3D) modelling has become essential in the heritage field, but static models cannot capture how heritages evolve over time. To this end, more and more studies have presented four-dimensional (4D, i.e., 3D + time) applications.
Yibin Hu, Bo Gao, Haoxi Chen
doaj   +1 more source

Land cover type modulates the distribution of litter in a Nordic cultural landscape. [PDF]

PLoS One, 2022
Eide SKK, Leh LN, Eines KS, Hovland I, By M, Ingvaldsen EW, Tinlund M, Emerita E, Machado LA, Brønner S, Nilsen EB, Steyaert SMJG.   +11 more
europepmc   +1 more source

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

The role of Medieval road operation on cultural landscape transformation. [PDF]

Sci Rep, 2021
Słowiński M, Brauer A, Guzowski P, Związek T, Obremska M, Theuerkauf M, Dietze E, Schwab M, Tjallingii R, Czaja R, Ott F, Błaszkiewicz M.   +11 more
europepmc   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

Advanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba, Sang‐Hyeok Lee, Christina Gasper, Martina Freund, Sandra Korte‐Kerzel, Ulrich Kerzel   +5 more
wiley   +1 more source

Sustainable Development Efficiency of Cultural Landscape Heritage in Urban Fringe Based on GIS-DEA-MI, a Case Study of Wuhan, China. [PDF]

Int J Environ Res Public Health, 2022
Zou H, Liu Y, Li B, Luo W.
europepmc   +1 more source

Historical Foundation and Practical Guideline for Ferroelectric Switching Kinetic Studies

Advanced Functional Materials, EarlyView.
The P and U pulses in the conventional PUND measurements are not identical because of the interplay between switching current and the measurement circuit components. This circuit effect can lead to a shift in polarization transients and misinterpreted physics in the switching kinetics.
Yi Liang, Pat Kezer, John T. Heron
wiley   +1 more source

Botanical Gardens and Arboretums as Regards to Cultural Landscapes: Three Cases from Istanbul

Journal of Architectural Sciences and Applications
The aim of the study is to examine Istanbul University Alfred Heilbronn Botanical Garden, Atatürk Arboretum and Nezahat Gökyiğit Botanical Garden as examples of cultural landscapes and to determine which cultural landscape criteria they reflect.
Meryem Atik, Betül Tülek, Ayşe Durak, Sümeyra Elma   +3 more
doaj   +1 more source