Results 71 to 80 of about 72,601 (261)
Model of interaction of geographic, cultural and sacral landscapes
The interaction of geographical, cultural and sacred landscapes is considered. The concept “landscape” is analyzed and its interdisciplinary character is emphasized. It is proposed to divide the definition of phenomenon on the concept “theoretical models”
Nataliya Nikolaevna LAVRINOVA
doaj
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Necrology: Professor P.R. Sharma (1950 – 2020)
Rana P.B. Singh
doaj +1 more source
Digital afterlives: Tracing the resurrection process of dead online cultures
In this article, we discuss the different dynamics of the resurrection process of “dead” online cultures and objects. We have previously defined four life phases of online objects (active, passive, zombie, haunting), and this article adds resurrection as
Sihvonen Lilli, Vaahensalo Elina
doaj +1 more source
Empowering Adult Learning How AI Fuels Progress Across Disciplines and Professions
ABSTRACT This article examines the evolving role of artificial intelligence (AI) as a transformative cognitive partner across educational and professional fields. It explores how AI shifts attention away from routine technical tasks and toward human‐centered skills such as critical thinking, ethical decision‐making, and professional judgment.
Rachel Wlodarsky
wiley +1 more source
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Cultural landscape perception of the Chinese traditional settlement: Based on tourists' online comments. [PDF]
Zhou J, Wu S, Wu X, Xia X.
europepmc +1 more source

