Results 81 to 90 of about 4,310,481 (293)

Cultural Landscapes: Exploring the Imprint of the Roman Empire on Modern Identities

Land
This study explores how cultural landscapes serve as dynamic interfaces between human societies and their environments, reflecting intricate interactions shaped by historical and societal changes.
Marianna Olivadese, Maria Luisa Dindo
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Tourisme et paysages culturels : comparaison de la Valeur universelle exceptionnelle et de la mise en récit institutionnelle (UNESCO) de trois sites latino-américains

IdeAs, 2018
Cultural landscapes, conceived by UNESCO as the combined works of man and nature, became an operating category of World Heritage in 1992. This article analyzes, through a comparative study, the processes of heritage, narrative and tourism in three ...
Elodie Salin
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

The Comprehensive Live Cell‐Based Cytotoxicity Assay for Monitoring Disease Activity and Guiding Rescue Therapy in Acute Attacks of NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a devastating neurological disease that lacks serological biomarkers that can accurately reflect disease activity. We established a live cell‐based assay (LCBA) using serum with endogenous complement to quantify the overall cytotoxicity, offering a novel functional tool for monitoring
Xiaona Xu, Jie Ding, Yupeng Du, Guibao Luo, Jinming Li, Rui Liu, Xiaoyi Xu, Xiao Li, Minshu Li, Wei Jiang, Chunsheng Yang   +10 more
wiley   +1 more source

The railway heritage in Mexico and its role in the configuration of industrial and cultural landscapes [PDF]

, 2016
The construction of the railways in Mexico was an event of national importance, not only for its role in the economic history, but for their contribution in shaping cultural landscapes of industrial character.
Michel-Estrada, Gabriel, Solórzano-Gil, Mónica   +1 more
core  

Stage‐Specific Patterns of Imaging and Non‐Motor Biomarkers in Spinocerebellar Ataxia Type 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Advancements in disease‐modifying therapies for spinocerebellar ataxia Type 3 (SCA3) underscore the need for robust biomarkers to monitor disease progression and evaluate treatment efficacy. Although motor phenotypes have been well characterized, less is known about non‐motor and imaging‐based features across different disease stages.
Chun Li, Zhi‐Xian Ye, Xuan‐Yu Chen, Liang‐Liang Qiu, Zhi‐li Chen, Yu‐Sen Qiu, Wei Lin, Ru‐Ying Yuan, Xin‐Tong Yu, Chun‐Yu Huang, Xin‐Yuan Chen, Min‐Ting Lin, Jian‐Ping Hu, Wan‐Jin Chen, Ning Wang, Shao‐Bo Yao, Shi‐Rui Gan, Ying Fu   +17 more
wiley   +1 more source

Cap. V Planning the future of European agricultural landscapes considering their cultural value and heritage

, 2010
the main aim of working group 5 was to consider cultural values and heritage in European agriculrtural landscapes. The group catalogued different european views on the cultural values of agricultural landscapes and organised these views into guidelines ...
M. Dobrovovodska, J. Spulerova, M. Buchecker, C. Steiner, A. Schabl, Z. Mavar, B. Martinovic Vukovic, M. Dolores Velarde, PUNGETTI, GLORIA, SCAZZOSI, LIONELLA, MARZORATI, PAOLA, A. Kruse, M. Roth, ROBBIATI, CINZIA, E. Raguz Lucic   +14 more
core  

Molecular Diagnosis in Children With Febrile Seizures: Beyond the Conventional Clinical Classification

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Febrile seizures (FS) are currently classified as simple or complex primarily to describe seizure characteristics, with limited ability to identify the underlying etiology. We evaluated whether molecular diagnosis could complement conventional classification and improve the diagnosis and management of FS.
Jia Wang, Mengna Zhang, Yangyang Wang, Xiuyu Shi, Baoguang Li, Xiuxia Wang, Dan Sun, Sanqing Xu, Jianbo Zhao, Lijun Du, Qiming Pang, Xiaoming Liu, Chunhui Tang, Xiaohua Li, Jiuwei Li, Yanli Ma, Jianxiang Liao, Gulixian Abudureyimu, Jianmin Liang, Yuan Wang, De Wu, Jian Wu, Liping Zou   +22 more
wiley   +1 more source

KARELIA: Cultural Landscapes, the evolution of landscapes

, 2018
The studio course “Cultural Landscapes: the evolution of landscapes” was organized by the Aalto University Landscape Architecture programme in the spring term 2016 and explored the concept of cultural landscape, not as a particular type of designated and
Galan Vivas, Juanjo
core   +1 more source