Results 61 to 70 of about 375,404 (307)

Du socle au paysage : essai pour un nouveau regard sur les reliefs

open access: yesProjets de Paysage, 2012
This paper studies the geomorphic component of “landscapes artialisation” by studying the major landforms in landscapes’ representations. Landforms are considered here as landscapes patterns constituting the "geographical basement " for landscape painter,
Claire Portal
doaj   +1 more source

Girls’ access to education in China: actors, cultures and the windmill of development management [PDF]

open access: yes, 2010
The world has a mixed record towards achieving EFA and the MDGs in relation to the targets on gender equity in basic education. For researchers and practitioners, this raises the question of which factors influence the processes leading to the ...
Wang, Xiaojun Grace
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The hidden cultural impact of climate-driven food security threats to landscapes

open access: yesCell Reports Sustainability
Climate change could severely affect traditional diets, ceremonies, and landscapes, eroding cultural identity and heritage. Some landscapes are unique because they reflect cultural identity linked to diet (e.g., rice terraces).
Paolo Tarolli   +8 more
doaj   +1 more source

Semiotic of Cultural Landscapes in Cultural Geography; a Conceptual Approach for Detection and understanding Meaning [PDF]

open access: yesTaḥqīqāt-i Farhangī-i Īrān, 2012
Studying the Location and spatial performances as a part of human behavioris discussed in semiotics nowadays. These man-made effectsare including information and meaning that is the subject of semiotics.
Ebrahim Fayaz   +2 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Northern peripheries [PDF]

open access: yes, 2013
Guest editors ...
Ejlerskov, Katrine Tschentscher   +5 more
core   +3 more sources

Does Greek Conservation Policy Effectively Protect the Cultural Landscapes? A Critical Examination of Policy’s Efficiency in Traditional Greek Settlements [PDF]

open access: yes, 2014
The first part focuses on the legislative framework, providing a critical examination regarding the way that cultural landscape is approached. The second part discusses the effects of this policy on a group of traditional settlements in central Greece ...
Katapidi, Ioanna
core   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Viticultural landscapes in transition: permanence and change

open access: yesMiscellanea Geographica: Regional Studies on Development, 2018
This article concerns the transitions of cultural landscapes, especially of viticultural landscapes. The authors do not aim to present new definition of the term “landscape” but base their study on the existing output of Polish and foreign scholars.
Miętkiewska-Brynda Joanna   +1 more
doaj   +1 more source

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