Results 71 to 80 of about 375,404 (307)
Far-Sightedness vs. Emergency: A Matter for “Not Outstanding” European Cultural Landscapes
Buildings, 2018 A far-sighted policy, designed to safeguard a State’s land and culture, is one that would be able to go beyond emergency culture in the direction of shared far-sightedness in the territorial government, looking ahead to future generations.
Rossella Salerno
doaj +1 more source
Land, 2020 Mediterranean cultural landscapes have been recognized as multifunctional landscapes that are currently threatened by two opposing trends: rural abandonment and agricultural intensification.
Íñigo Bidegain +5 more
doaj +1 more source
Japan Architectural Review, 2022 Cultural landscapes of vineyards and wineries are often evaluated based on their relationships to natural conditions or “terroir.” However, in vernacular evaluation, their meaning may need to be interpreted in the wider context of the region beyond the ...
Yoshito Kikuchi
doaj +1 more source
Biodiversity performance of organic farms in Austria - results from eight years of biodiversity assessment [PDF]
, 2018 Assessing the biodiversity performance of agricultural farms has gained importance in recent years since conserving and promoting biodiversity and associated ecosystem functions in cultural landscapes is a key aspect in making agriculture more ...
Drapela, T. +4 more
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
BuildingsAs a World Cultural Heritage site, the Beijing–Hangzhou Grand Canal is lined with historic and cultural cities that bear abundant historical and cultural connotations.
Pengfei Du +7 more
doaj +1 more source
Methodological advances in the analysis, assessment and intervention of industrial landscapes [PDF]
, 2018 We are currently witnessing a gradual extension of the concept of heritage. This idea has evolved to encompass landscapes and is even reaching into an area which, until recently, had not received sufficient attention: industrial heritage. This new notion
Alba-Dorado, Maria Isabel
core
FEBS Open Bio, EarlyView.A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source