Results 21 to 30 of about 10,059 (261)

Involving the Community in Inner City Renewal: A Case Study of Nanluogu in Beijing

open access: yesJournal of Urban Management, 2012
: Robust economic growth and rapid urbanization led many Chinese cities to embark upon some of the world's largest inner city renewal projects. The official goal of inner city neighborhood redevelopment is to improve quality of life; however, it has ...
Chun Zhang, Bin Lu, Yan Song
doaj   +1 more source

The Impact of Urban Community Renewal on Residents' Subjective Well-Being: An Empirical Study Based on Typical Communities in Nanjing

open access: yesRedai dili, 2023
Urban community renewal is committed to improving the material, socioeconomic, and cultural environments of the community and satisfying people's pursuit of a better life.
Wang Zhen, Zhang Min
doaj   +1 more source

Perspectives on the Religion–Culture Relationship in a Globalized Secular Culture According to Christopher Dawson

open access: yesReligions
This article explores the interplay between religion and culture in Christopher Dawson’s philosophy of history and underlines the relevance of his analysis in today’s globalized culture, which often shows little interest in religion.
Rubén Herce
doaj   +1 more source

Islamization as a Force of Global Cultural Renewal or

open access: yesAmerican Journal of Islam and Society, 1988
Islamization constitutes a major force of renovation upon the contemporary world scene. A little over a decade ago, the mid-seventies witnessed a heightened awareness of Islamic cultural identity among the Ummah worldwide, an awareness which was ...
Mona Abul Fadl
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

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