Results 31 to 40 of about 6,071,112 (296)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Student Engagement in Peer Dialogue About Diversity and Inclusion
Journal of Occupational Therapy Education, 2020 Student engagement in peer dialogue is a key aspect of a transformative learning process. However, the dynamics of peer dialogue become more complex when applied to concepts of diversity and inclusion, due to increased risk of student vulnerability and ...
Barry L. Trentham +7 more
doaj +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Indigenous Methodology in Understanding Indigenous Nurse Graduate Transition to Practice
International Indigenous Policy Journal, 2017 Increasing Indigenous health care professional presence in health care aims to reduce health inequities of Indigenous Peoples in Canada. Nurses are the largest health professional group and nurse graduates the main source of recruitment.
Donna L. M. Kurtz +4 more
doaj +1 more source
Teaching Cultural Safety the Culturally Safe Way [PDF]
, 2001 The concept of cultural safety emerged in New Zealand in the late 1980s as a response to the differential health experience and negative health outcomes of Māori, the first nation people of New Zealand.
Lynda Jeffs
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The future of process safety [PDF]
, 2017 PresentationProcess safety has been practiced for several decades, but it is only in recent years that it has become an established discipline. During this evolution we have seen the development of risk assessment techniques and inherently safer design.
Kerin, Trish
core +1 more source
Colonial Legacies and Collaborative Action: Improving Indigenous Peoples’ Health Care in Canada
International Indigenous Policy Journal, 2020 Indigenous people experience significant health disparities compared to non-Indigenous people, which are exacerbated by less accessible and poorer quality health care services.
Lloy Wylie +2 more
doaj +1 more source
Forest Science and Technology, 2021 Zelkova serrata (Thunb.) Makino trees, which account for a large proportion of cultural assets and protected trees and have considerable historical and cultural symbolic meaning in South Korea.
Jiwon Son +4 more
doaj +1 more source