Results 41 to 50 of about 6,322,087 (302)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Teaching Cultural Safety the Culturally Safe Way [PDF]
, 2001 The concept of cultural safety emerged in New Zealand in the late 1980s as a response to the differential health experience and negative health outcomes of Māori, the first nation people of New Zealand.
Lynda Jeffs
core
Indigenous Methodology in Understanding Indigenous Nurse Graduate Transition to Practice
International Indigenous Policy Journal, 2017 Increasing Indigenous health care professional presence in health care aims to reduce health inequities of Indigenous Peoples in Canada. Nurses are the largest health professional group and nurse graduates the main source of recruitment.
Donna L. M. Kurtz +4 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The future of process safety [PDF]
, 2017 PresentationProcess safety has been practiced for several decades, but it is only in recent years that it has become an established discipline. During this evolution we have seen the development of risk assessment techniques and inherently safer design.
Kerin, Trish
core
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Forest Science and Technology, 2021 Zelkova serrata (Thunb.) Makino trees, which account for a large proportion of cultural assets and protected trees and have considerable historical and cultural symbolic meaning in South Korea.
Jiwon Son +4 more
doaj +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Advances in Materials Science and Engineering, 2021 The silty clay in the lower reaches of the Yellow River is characterized by loose structure, low strength, and strong capillary effect. Based on the technology of ancient glutinous rice mortar and microbial-induced calcium carbonate precipitation (MICP),
Jianwei Yue +5 more
doaj +1 more source