Results 41 to 50 of about 208,549 (309)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Indigenous Methodology in Understanding Indigenous Nurse Graduate Transition to Practice

open access: yesInternational Indigenous Policy Journal, 2017
Increasing Indigenous health care professional presence in health care aims to reduce health inequities of Indigenous Peoples in Canada. Nurses are the largest health professional group and nurse graduates the main source of recruitment.
Donna L. M. Kurtz   +4 more
doaj   +1 more source

Cultural safety: A resource for, or, a challenge to our practice? [PDF]

open access: yes, 2011
This presentation explored discursive effects of cultural safety identified in my doctoral ...
Crocket, Alastair
core  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

The Cultural Construction of Safety and Security

open access: yes
This volume analyses cultural perceptions of safety and security that have shaped modern European societies. The articles present a wide range of topics, from feelings of unsafety generated by early modern fake news to safety issues related to twentieth ...

core   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cross-cultural Adaptation of the Safety Attitudes Questionnaire Short Form in Spanish and Italian Operating Rooms: Psychometric Properties [PDF]

open access: yes, 2022
Objectives The aims of the study were to translate the Safety Attitudes Questionnaire Short Form (SAQ-SF) in Spanish and Italian surgical settings and to assess its psychometric properties.
Bernalte-Martí, Vicente
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Exploring how Australian general practice registrars define cultural safety with Aboriginal and Torres Strait Islander patients: a mixed method study. [PDF]

open access: yesBMC Prim Care
Background Understanding how the general practice medical workforce defines cultural safety may help tailor education and training to better enable community-determined culturally safe practice.
Brumpton K   +6 more
europepmc   +2 more sources

The future of process safety [PDF]

open access: yes, 2017
PresentationProcess safety has been practiced for several decades, but it is only in recent years that it has become an established discipline. During this evolution we have seen the development of risk assessment techniques and inherently safer design.
Kerin, Trish
core  

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