Results 151 to 160 of about 17,762,594 (353)

The human body: From its instrumentality to its axiological precedence in the contemporary art of design [PDF]

open access: yes, 2015
Heidegger’s notion of ‘handiness’ combines two meanings, which in my view should be separated. They both refer to ways of characterizing tools in a given culture. Every culture uses tools, and they are all used so they are ‘handy’. The question is: Handy
Staniszewska, Elżbieta
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Cultural Values In The Film 'Najih' By Pondok Pesantren Dalwa Charles Sanders Peirce's Semiotic Analysis

open access: yesJurnal Studi Agama
This research aims to describe the cultural values contained in the film "Najih" by Pondok Pesantren Dalwa. The film Najih tells the story of a young man who is determined and never gives up in his journey to learn Arabic. This research is a qualitative
Alfina Hartono   +2 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

BÉLETER FOR TRANSFERRING LANGUAGE AND CULTURAL MORAL VALUES TO YOUNG MALAY AT PONTIANAK, KALIMANTAN BARAT. [PDF]

open access: yes, 2011
Bahasa adalah alat komunikasi yang menyampaikan setiap perasaan penuturnya. Ia bisa menyampaikan perasaan sayang, cinta, suka, benci, kecewa, bahkan marah.
Syarifah , Lubna
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Benefit transfers of cultural heritage values - how far can we go? [PDF]

open access: yes
Assessing the economic values attached to alternative land uses, when cultural heritage goods are at stake, makes the valuation process more articulated. Economic elicitation of cultural heritage values is quite a recent practice.
Patrizia Riganti, Peter Nijkamp
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

THE EFFECT OF PERSONAL AND PROFESSIONAL CULTURAL VALUES TOWARDS THE MARKETING ETHICS OF ACADEMICIANS

open access: yesJurnal Riset Manajemen Sains Indonesia, 2011
This study assesses the personal cultural values and professional values of academicians in regards to marketing ethics. This research uses Singhapakdi and Vitell’s (1993) marketing norms scale and professional value scale together with Yoo and Donthu’s (
Chuah Chin Wei   +2 more
doaj  

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