Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Is It a Just World After All? Age Differences in the Belief in a Just World Across 57 Societies and the Influences of Cultural Values. [PDF]
Li T, Guo N, Luo W.
europepmc +1 more source
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Unique cultural values of Madura cattle : is crossbreeding a threat?
In Indonesia, crossbreeding local cattle with European beef breeds is widely promoted to stimulate beef production. Crossbreeding is threatening local breeds which have often multiple functions, including cultural roles.
Widi, T.S. Mastuti
core
Asian cultural values and help-seeking: a cross-sectional study on compulsive sexual behavior. [PDF]
Pham HL +10 more
europepmc +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Investigation of individual cultural values and perceived gender role on disaster management in Generation Z earthquake victims. [PDF]
Akkaş I +3 more
europepmc +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Cross-cultural perspectives on social difficulties and anxiety in youth: the role of family cultural values in Mexico and Italy. [PDF]
Galán-Vera IZ +3 more
europepmc +1 more source
Ethnic pride and cultural values promote positive youth development in a conceptual replication of the Five Cs model. [PDF]
Johnson LE +3 more
europepmc +1 more source

