Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Is It a Just World After All? Age Differences in the Belief in a Just World Across 57 Societies and the Influences of Cultural Values. [PDF]
Li T, Guo N, Luo W.
europepmc +1 more source
Ethnic pride and cultural values promote positive youth development in a conceptual replication of the Five Cs model. [PDF]
Johnson LE +3 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Asian cultural values and help-seeking: a cross-sectional study on compulsive sexual behavior. [PDF]
Pham HL +10 more
europepmc +1 more source
The Influencing Role of Cultural Values on Attitudes of the Chinese Public Towards Traditional Chinese Medicine (TCM) for the Control of COVID-19. [PDF]
Zhao H, Zhang R, Chen Y.
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Investigation of individual cultural values and perceived gender role on disaster management in Generation Z earthquake victims. [PDF]
Akkaş I +3 more
europepmc +1 more source
The impact of pandemic mental cognition on cultural values: an empirical study based on social media. [PDF]
Mo L, Liu Y, Li A, Liu T, Zhu T.
europepmc +1 more source

