Results 111 to 120 of about 8,418,026 (404)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Implementing Energy Efficiency & ESD from a Development Perspective [PDF]
, 2004 This note discusses the difficulties currently being experienced in implementing Ecological Sustainable Development (ESD) from a development perspective. It looks at what motivates developers and examines what is needed, either through mandatory measures
Hood, David A.
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Popüler Kültür ve Müzikte Anlamın Kaybı
Akademik İncelemeler Dergisi, 2015 Avrupa’da 17. yüzyıldan itibaren başlayan ekonomik, toplumsal, siyasal ve sosyal alanda yaşanan köklü değişimlerin ifadesi olan modernite, zamanla tüm dünyayı etkisi altına almıştır. Pek çok alanla birlikte özellikle kültür anlayışı ve sanata yansımaları
Mehmet Birekul
doaj +1 more source
Analysis of the Application of Sundanese Batik in the Interior of the Grand Preanger Hotel [PDF]
, 2019 At first batik was known as a patterned cloth that contains a high philosophy which is one of Indonesian culture. The ability of batik to adapt to the times makes batik develop in terms of application.
Joshua, I. (Ivan ) +1 more
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
A Little Death Around the Eyes
Kulturella Perspektiv, 2009 This article discusses the relationship between pre-romantic Anglo-Saxon literature, iconology in late modern music industry, artistry performance and heroin abuse in Pete(r) Doherty's musical universe. Through the concept of 'autofiction' which include
Sarah Holst Kjær
doaj +1 more source
The Fine Art of Commercial Freedom: British Music Videos and Film Culture [PDF]
, 2014 An outline and analysis of the British music video industry and its impact on film culture in the 1990s and ...
Caston, Emily
core
MANAGEMENT APPROACHES FOR INDUSTRY 4.0 – THE ORGANIZATIONAL CULTURE PERSPECTIVE
Technological and Economic Development of Economy, 2018 The Industry 4.0 concept describes a decentralized production chain that extends from design to the supply chain, production, distribution as well as customer service.
Hana Mohelská, M. Sokolová
semanticscholar +1 more source